7,14- dihydroxydocosa- 4,8,10,12,16,19- hexaenoic acid

02/01/2015 - "In this study, metabololipidomics of murine lungs identified temporal changes in endogenous maresin 1 (MaR1) during self-limited allergic inflammation. "
03/23/2023 - "This hydroperoxidation reaction is followed by an epoxidation and hydrolysis process that finally leads to maresin 1 (MaR1), a potent bioactive specialized pro-resolving mediator (SPM) in chronic inflammation resolution. "
10/01/2022 - "Maresin 1 (MaR1), a specialized pro-resolving mediators (SPMs), is biosynthesised in macrophages (Mφs) that regulates acute inflammation. "
01/01/2021 - "Maresin 1 (MaR1) is a specialized proresolving mediator produced during the resolution of inflammation. "
10/01/2020 - "Maresin 1 resolves aged-associated macrophage inflammation to improve bone regeneration."

01/01/2018 - "Maresin 1 (MaR1) is a newly identified member of PRMs, and recent studies implicate its potential role in some pain conditions. "
01/01/2015 - "Thus, maresin 1 may serve as a novel endogenous inhibitor for treating TMJ-inflammatory pain in the orofacial region. "
04/01/2012 - "Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain."
01/01/2023 - "We evaluated the effects of oral treatment with the SPM Maresin 1 (MaR1) on behavioral pain responses and spinal neuroinflammation in male and female C57BL/6J mice with spared nerve injury (SNI)-induced NP. "
10/01/2021 - "Using a murine vulvar pain model, coupling proinflammatory mediator quantification with mechanical sensitivity threshold determination, topical treatment with the SPM, maresin 1, decreased sensitivity and suppressed PGE2 levels. "

02/02/2022 - "Maresin 1 promotes nerve regeneration and alleviates neuropathic pain after nerve injury."
01/01/2018 - "Pro-resolving mediator maresin 1 ameliorates pain hypersensitivity in a rat spinal nerve ligation model of neuropathic pain."
01/01/2023 - "The pro-resolving lipid mediator Maresin 1 ameliorates pain responses and neuroinflammation in the spared nerve injury-induced neuropathic pain: A study in male and female mice."

01/01/2017 - "Maresin 1 Ameliorates Lung Ischemia/Reperfusion Injury by Suppressing Oxidative Stress via Activation of the Nrf-2-Mediated HO-1 Signaling Pathway."
01/01/2021 - "Maresin 1 protects the liver against ischemia/reperfusion injury via the ALXR/Akt signaling pathway."
01/01/2019 - "Maresin 1 mitigates renal ischemia/reperfusion injury in mice via inhibition of the TLR4/MAPK/NF-κB pathways and activation of the Nrf2 pathway."
01/15/2020 - "Maresin 1, a Proresolving Lipid Mediator, Ameliorates Liver Ischemia-Reperfusion Injury and Stimulates Hepatocyte Proliferation in Sprague-Dawley Rats."
03/25/2016 - "The pro-resolving lipid mediator Maresin 1 protects against cerebral ischemia/reperfusion injury by attenuating the pro-inflammatory response."

01/01/2022 - "Maresin 1 improves cognitive decline and ameliorates inflammation and blood-brain barrier damage in rats with chronic cerebral hypoperfusion."
01/01/2022 - "Therefore, we discussed the impact of the macrophage mediator in resolving inflammation 1 (Maresin 1) on the CCH-induced cognitive impairment and its underlying mechanisms. "
01/01/2019 - "Maresin 1 Improves Cognitive Decline and Ameliorates Inflammation in a Mouse Model of Alzheimer's Disease."