butyzamide

an orally bioavailable non-peptidyl thrombopoietin receptor, Mpl activator; structure in first source

Also Known As:

(E)-3-(2,6-dichloro-4-(4-(3-(2,2-dimethyl-1-propoxypropyl)phenyl)-thiazol-2-ylcarbamoyl)phenyl)-2-methylacrylic acid

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Thrombocytopenia (Thrombopenia) 10/01/2008 - "Butyzamide is an orally bioavailable human Mpl activator, and appears to have potential for clinical development as a therapeutic agent for patients with thrombocytopenia."
2.	Polyploidy 10/01/2008 - "Butyzamide induced colony-forming unit-megakaryocytes and polyploid megakaryocytes from human CD34(+) hematopoietic progenitor cells, and its effects were comparable to those of thrombopoietin. "

1.	Thrombopoietin (c-mpl Ligand)