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calotropone

from Calotropis gigantea; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - Pregnanolone: 560
        calotropone: 1

Experts

1.	Ahmad, Khairunnas: 1 article (01/2022)
2.	Hasballah, Kartini: 1 article (01/2022)
3.	Iqhrammullah, Muhammad: 1 article (01/2022)
4.	Mardina, Vivi: 1 article (01/2022)
5.	Purnama, Agnia: 1 article (01/2022)
6.	Puspita, Kana: 1 article (01/2022)
7.	Qanita, Intan: 1 article (01/2022)
8.	Rizki, Diva Rayyan: 1 article (01/2022)

Related Diseases

1.	Pancreatic Neoplasms (Pancreatic Cancer) 01/01/2022 - "Molecular docking investigation of calotropone as a potential natural therapeutic agent against pancreatic cancer." 01/01/2022 - "A natural bioactive compound named calotropone has been reported as a drug candidate for several cancers, including pancreatic cancers. " 01/01/2022 - "By employing AutoDock Vina, we studied the molecular interaction between calotropone and pancreatic cancer-associated proteins, namely Glucosaminyl (N-Acetyl) Transferase 3, Glutamic-Oxaloacetic Transaminase 1, Tyrosine-protein kinase Met (c-Met), peroxisome proliferator-activated receptor γ, Budding Uninhibited by Benzimidazole 1, A Disintegrin and Metalloproteinase 10, Sex-determining region Y and Nuclear Factor kappa Beta (Nf-Kβ). "
2.	Neoplasms (Cancer) 01/01/2022 - "A natural bioactive compound named calotropone has been reported as a drug candidate for several cancers, including pancreatic cancers. " 01/01/2022 - "Herein, we used molecular docking approach to test the possible mechanisms of action of calotropone in inhibiting the growth of pancreatic cell cancer with gemcitabine as the positive control. "

Related Drugs and Biologics

1.	Peroxisome Proliferator-Activated Receptors (PPAR)
2.	Metalloproteases (Metalloproteinases)
3.	Disintegrins
4.	Transferases
5.	Proteins (Proteins, Gene)
6.	Protein-Tyrosine Kinases (Tyrosine Kinase)
7.	Aspartate Aminotransferases (Aspartate Transaminase)
8.	Gemcitabine
9.	benzimidazole