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ganoderic acid Me

an antimetastasis agent that causes down-regulation of MMP-2/9; isolated from Ganoderma lucidum

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - ganoderic acid Me: 6

Experts

1.	Liu, Jianwen: 2 articles (11/2014 - 06/2007)
2.	Zhong, Jian-Jiang: 2 articles (10/2008 - 06/2007)
3.	Chen, Nianhong: 1 article (01/2022)
4.	Wan, Guoqing: 1 article (01/2022)
5.	Zeng, Xiaobin: 1 article (01/2022)
6.	Bi, Ling: 1 article (11/2014)
7.	Que, Zujun: 1 article (11/2014)
8.	Tian, Jianhui: 1 article (11/2014)
9.	Zhang, Anle: 1 article (11/2014)
10.	Zheng, Yuanhong: 1 article (11/2014)

Related Diseases

1.	Neoplasms (Cancer) 10/01/2012 - "In the present study, we looked into the effect of ganoderic acid Me (GA-Me) on cellular phenotypes and tumor growth in the MDA-MB-231 breast cancer cell line. " 10/24/2012 - "Enhanced ganoderic acid Me (GA-Me, an important anti-tumor triterpene) yield was attained with the medicinal fungus Ganoderma lucidum using response surface methodology (RSM). " 10/01/2008 - "Ganoderic acid Me inhibits tumor invasion through down-regulating matrix metalloproteinases 2/9 gene expression." 06/01/2007 - "Ganoderic acid Me (GA-Me) is a lanostane triterpenoid purified from Ganoderma lucidum mycelia, one of the most widely used herbs for cancer treatment and prevention in east Asia. " 06/01/2007 - "Enhancement of IL-2 and IFN-gamma expression and NK cells activity involved in the anti-tumor effect of ganoderic acid Me in vivo."
2.	Breast Neoplasms (Breast Cancer) 10/01/2012 - "In the present study, we looked into the effect of ganoderic acid Me (GA-Me) on cellular phenotypes and tumor growth in the MDA-MB-231 breast cancer cell line. "
3.	Colorectal Neoplasms (Colorectal Cancer) 01/01/2022 - "Integrated Whole-Transcriptome Profiling and Bioinformatics Analysis of the Polypharmacological Effects of Ganoderic Acid Me in Colorectal Cancer Treatment."
4.	Lung Neoplasms (Lung Cancer) 11/01/2014 - "Ganoderic acid Me induces the apoptosis of competent T cells and increases the proportion of Treg cells through enhancing the expression and activation of indoleamine 2,3-dioxygenase in mouse lewis lung cancer cells."

Related Drugs and Biologics

1.	Triterpenes
2.	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)
3.	Matrix Metalloproteinases (MMPs)
4.	Interleukin-2 (IL2)