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3- (3- (3- florophenyl- 2- propyn- 1- ylthio)- 1,2,5- thiadiazol- 4- yl)- 1,2,5,6- tetrahydro-1-methylpyridine oxalate

xanomeline derivative that improved memory function in aged mice

Also Known As:

EUK1001

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - Thiadiazoles: 99
        3-(3-(3-florophenyl-2-propyn-1-ylthio)-1,2,5-thiadiazol-4-yl)-1,2,5,6- tetrahydro-1-methylpyridine oxalate: 2
  - Pyridines: 88
    - 3-(3-(3-florophenyl-2-propyn-1-ylthio)-1,2,5-thiadiazol-4-yl)-1,2,5,6- tetrahydro-1-methylpyridine oxalate: 2
Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazoles: 392
    - Thiadiazoles: 99
      - 3-(3-(3-florophenyl-2-propyn-1-ylthio)-1,2,5-thiadiazol-4-yl)-1,2,5,6- tetrahydro-1-methylpyridine oxalate: 2

Experts

1.	Dong, Suzhen: 1 article (11/2017)
2.	Duan, Yale: 1 article (11/2017)
3.	Jia, Kaili: 1 article (11/2017)
4.	Li, Ziyan: 1 article (11/2017)
5.	Wang, Dong: 1 article (11/2017)
6.	Zhou, Zongli: 1 article (11/2017)
7.	Cao, Xiaohua: 1 article (04/2010)
8.	Chen, Huanxin: 1 article (04/2010)
9.	Lei, Xiaoping: 1 article (04/2010)
10.	Niu, Yan: 1 article (04/2010)

Related Diseases

1.	Alzheimer Disease (Alzheimer's Disease) 04/05/2010 - "Thus, EUK1001 may possibly represent a promising lead compound for the treatment of Alzheimer's disease and age-related cognitive deficits." 11/01/2017 - "Xanomeline derivative EUK1001 attenuates Alzheimer's disease pathology in a triple transgenic mouse model."
2.	Cognitive Dysfunction 11/01/2017 - "These results demonstrate that EUK1001 may ameliorate the cognitive dysfunction of AD mice, possibly by reducing Aβ production. "

Related Drugs and Biologics

1.	xanomeline