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pongamol

from Pongamia pinnata fruits; structure in first source

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzofurans: 26
      - pongamol: 3

Experts

1.	Chanvorachote, Pithi: 1 article (12/2021)
2.	Putri, Hardyanti Eka: 1 article (12/2021)
3.	Sritularak, Boonchoo: 1 article (12/2021)
4.	Jain, Alok Pal: 1 article (09/2016)
5.	Jain, Avijeet: 1 article (09/2016)
6.	Lodhi, Santram: 1 article (09/2016)
7.	Pawar, Rajesh Singh: 1 article (09/2016)
8.	Singhai, Abhay Kumar: 1 article (09/2016)

Related Diseases

1.	Wounds and Injuries (Trauma) 09/01/2016 - "Luteolin and pongamol ointments were also found to be effective in both wound models. "
2.	Neoplasms (Cancer) 12/01/2021 - "Regarding anoikis resistance potential, the compound significantly inhibited survival and growth of cancer cells in an anchorage-independent manner, as indicated by the depletion of growing colonies in pongamol-pretreated cells. " 12/01/2021 - "Pongamol at 0-100 μM exhibited significant inhibition on migration, and invasion of cancer cells. " 12/01/2021 - "Pongamol exhibits potent anti-metastatic activity through suppressing key potentiating factors of cancer metastasis EMT and FAK."
3.	Neoplasm Metastasis (Metastasis) 12/01/2021 - "Pongamol exhibits potent anti-metastatic activity through suppressing key potentiating factors of cancer metastasis EMT and FAK." 12/01/2021 - "Protein level analysis further showed that pongamol exerted its anti-metastasis effect by inhibiting EMT, as indicated by a decrease of several mesenchymal proteins (N-cadherin, vimentin, Snail, and Slug). "
4.	Necrosis 12/01/2021 - "Apoptosis and necrosis induction in response to pongamol treatment was observed and visualized by nuclei staining assay. "
5.	Lung Neoplasms (Lung Cancer) 12/01/2021 - "We unraveled EMT inhibitory action of pongamol and the mechanism controlling cell dissemination in lung cancer cells. "

Related Drugs and Biologics

1.	Luteolin
2.	Ointments (Pastes)
3.	NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)
4.	Cadherins (E-Cadherin)
5.	Vimentin
6.	Proteins (Proteins, Gene)
7.	Isoflavones
8.	Chalcone (Benzalacetophenone)
9.	medicarpin
10.	inermin