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human MIRN186 microRNA

downregulates P2X7 receptor expression; GenBank AJ560752

Also Known As:

MIRN186 microRNA, human; hsa-mir-186; miR-186, human; miR-186-5p, human; microRNA-186, human

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleic Acids: 11752
  - RNA: 69704
    - Untranslated RNA: 2850
      - Small Untranslated RNA: 566
        MicroRNAs: 67298
        human MIRN186 microRNA: 5
    - Antisense RNA: 1599
      - MicroRNAs: 67298
        human MIRN186 microRNA: 5
- Antisense Elements (Genetics): 31
  - Antisense RNA: 1599
    - MicroRNAs: 67298
      - human MIRN186 microRNA: 5

Experts

1.	Aghajanian, Sepehr: 1 article (06/2021)
2.	Akhgar, Foruhar: 1 article (06/2021)
3.	Delrish, Nargess: 1 article (06/2021)
4.	Ehteshami, Maryam: 1 article (06/2021)
5.	Habibian-Sezavar, Fariba: 1 article (06/2021)
6.	Jazayeri, Seyed-Mohammad: 1 article (06/2021)
7.	Madihi, Mobina: 1 article (06/2021)
8.	Mozhgani, Sayed-Hamidreza: 1 article (06/2021)
9.	Norouzi, Mehdi: 1 article (06/2021)
10.	Ostadali, Mohammadreza: 1 article (06/2021)

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 05/01/2013 - "To explore the expression of hsa-mir-186 in colorectal cancer and study its role in regulating the biological behaviors of human colorectal cancer SW620 cells in vitro. "
2.	Neoplasms (Cancer) 05/01/2013 - "The relative expression of miR-186 in the cancer tissues was 0.0024∓0.0027, significantly lower than that in the adjacent tissues (0.066∓0.068, P=0.008); the relative expression level of hsa-miR-186 in SW620 and LoVo cells with a high metastatic potential was 0.118∓0.138 and 0.157∓0.001, respectively, significantly lower than that in HT-29 cells with a low metastatic potential (1.000∓0.00, P<0.05). " 04/06/2021 - "Cancer Cells' Metabolism Dynamics in Renal Cell Carcinoma Patients' Outcome: Influence of GLUT-1-Related hsa-miR-144 and hsa-miR-186." 01/01/2019 - "hsa-miR-186 overexpression is associated with metastatic cancers as well as arsenic-induced squamous cell carcinoma and is reported to target several mitotic regulators. "
3.	Carcinogenesis 11/15/2023 - "These results suggest that clonal variability mediates arsenic-induced carcinogenesis in hsa-miR-186 overexpressing human keratinocytes." 01/01/2019 - "This work investigates the potential aneuploidogenic role of hsa-miR-186 in arsenic carcinogenesis. "
4.	Chromosomal Instability (Chromosome Stability) 11/15/2023 - "Clonal variability in chromosomal instability as a potential driver in the acquisition of tumorigenic phenotype in chronic arsenic-exposed and hsa-miR-186 overexpressing human keratinocytes." 01/01/2019 - "Overexpression of hsa-miR-186 induces chromosomal instability in arsenic-exposed human keratinocytes."
5.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 11/15/2023 - "hsa-miR-186 is overexpressed in arsenic-induced squamous cell carcinoma relative to premalignant hyperkeratosis. " 01/01/2019 - "hsa-miR-186 overexpression is associated with metastatic cancers as well as arsenic-induced squamous cell carcinoma and is reported to target several mitotic regulators. "

Related Drugs and Biologics

1.	Arsenic
2.	human MIRN144 microRNA
3.	human MIrn181 microRNA