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3- (3- carboxybenzyl)- 1- ((6- ethylbenzo(d)(1,3)dioxol- 5- yl)methyl)- 6- hydroxy- 4- oxo- 1,4- dihydroquinoline- 2- carboxylic acid

Subscribe to New Research on 3-(3-carboxybenzyl)-1-((6-ethylbenzo(d)(1,3)dioxol-5-yl)methyl)-6-hydroxy-4-oxo-1,4-dihydroquinoline-2-carboxylic acid

a putative selective ETA-receptor antagonist

Also Known As:

HJP272

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 60
- 2-Ring Heterocyclic Compounds
  - Quinolines: 92
    - Hydroxyquinolines: 7
      - 3-(3-carboxybenzyl)-1-((6-ethylbenzo(d)(1,3)dioxol-5-yl)methyl)-6-hydroxy-4-oxo-1,4-dihydroquinoline-2-carboxylic acid: 2

Experts

1.	Stephani, Ralph: 2 articles (10/2014 - 08/2008)
2.	Liu, Xingjian: 1 article (10/2014)
3.	Patel, Shikha: 1 article (10/2014)
4.	Liu, Ming: 1 article (10/2014)
5.	Cantor, Jerome: 1 article (10/2014)
6.	Patel, Hardik: 1 article (10/2014)
7.	Olgun, Nicole: 1 article (08/2008)
8.	Wang, Wei: 1 article (08/2008)
9.	Reznik, Sandra E: 1 article (08/2008)
10.	Yen, Haoting: 1 article (08/2008)

Related Diseases

1.	Acute Lung Injury 10/01/2014 - "HJP272, a novel endothelin receptor antagonist, attenuates lipopolysaccharide-induced acute lung injury in hamsters."
2.	Lung Injury 10/01/2014 - "Treatment with HJP272 significantly reduced each of these parameters during a 24-hr period following LPS instillation, supporting the concept that limiting the activity of ET-1 may reduce the extent of lung injury. "
3.	Infection 08/01/2008 - "Effect of the putative novel selective ETA-receptor antagonist HJP272, a 1,3,6-trisubstituted-2-carboxy-quinol-4-one, on infection-mediated premature delivery."

Related Drugs and Biologics

1.	Endothelin Receptors (Endothelin Receptor)