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fispemifene

selective estrogen receptor modulator; structure in first source

Also Known As:

(Z)-2-(2-(4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy)ethoxy)ethanol

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzylidene Compounds: 10
        Stilbenes: 657
        Tamoxifen: 14288
        fispemifene: 2

Experts

1.	Bernoulli, Jenni: 1 article (10/2008)
2.	Lammintausta, Risto: 1 article (10/2008)
3.	Santti, Risto: 1 article (10/2008)
4.	Yatkin, Emrah: 1 article (10/2008)
5.	Häyry, Pekka: 1 article (11/2004)
6.	Kangas, Lauri: 1 article (11/2004)
7.	Luoto, Nina-Maria: 1 article (11/2004)
8.	Savolainen-Peltonen, Hanna: 1 article (11/2004)

Related Diseases

1.	Inflammation (Inflammations) 10/01/2008 - "Because fispemifene exhibited both antiestrogenic and anti-inflammatory action in the prostate, this experimental study suggests that SERMs could be considered as a new therapeutic option in the treatment and prevention of prostatic inflammation." 10/01/2008 - "Fispemifene significantly attenuated the glandular form of inflammation induced in the dorsolateral prostatic lobes (DLP) in the hormonal milieu of the decreased androgen/estrogen ratio. " 10/01/2008 - "The anti-inflammatory and antiestrogenic action of fispemifene [Z-2-{2-[4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy]ethoxy}-ethanol], a novel selective estrogen receptor modulator (SERM), was tested on the Noble rat model of chronic nonbacterial prostatic inflammation with cellular composition and inflammation patterns similar to those described in human prostatitis. " 10/01/2008 - "Fispemifene [Z-2-{2-[4-(4-chloro-1,2-diphenylbut-1-enyl)-phenoxy]ethoxy}-ethanol], a novel selective estrogen receptor modulator, attenuates glandular inflammation in an animal model of chronic nonbacterial prostatitis."
2.	Neointima 11/30/2004 - "Replacing the drug at 14 days with vehicle did not induce any rebound effect at 28 days, and furthermore, resulted in a smaller neointima with raloxifene and fispemifene. "
3.	Prostatitis 10/01/2008 - "The anti-inflammatory and antiestrogenic action of fispemifene [Z-2-{2-[4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy]ethoxy}-ethanol], a novel selective estrogen receptor modulator (SERM), was tested on the Noble rat model of chronic nonbacterial prostatic inflammation with cellular composition and inflammation patterns similar to those described in human prostatitis. " 10/01/2008 - "Fispemifene [Z-2-{2-[4-(4-chloro-1,2-diphenylbut-1-enyl)-phenoxy]ethoxy}-ethanol], a novel selective estrogen receptor modulator, attenuates glandular inflammation in an animal model of chronic nonbacterial prostatitis."

Related Drugs and Biologics

1.	Selective Estrogen Receptor Modulators (SERM)
2.	Raloxifene Hydrochloride (Evista)
3.	Estrogens (Estrogen)
4.	Androgens
5.	Ethanol (Ethyl Alcohol)