HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

tyrosyl- glycyl- phenylalanyl- leucyl- (O- lactosyl)serinamide

a lactomorphinan opioid agonist

Also Known As:

MMP 2200; MMP-2200; MMP2200; Tyr-Gly-Phe-Leu-(O-lactosyl)Ser-NH2

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycopeptides: 1928
    - tyrosyl-glycyl-phenylalanyl-leucyl-(O-lactosyl)serinamide: 3
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Glycopeptides: 1928
    - tyrosyl-glycyl-phenylalanyl-leucyl-(O-lactosyl)serinamide: 3

Experts

1.	Polt, Robin: 3 articles (10/2018 - 09/2008)
2.	Falk, Torsten: 2 articles (10/2018 - 09/2011)
3.	Porreca, Frank: 2 articles (10/2018 - 09/2011)
4.	Sherman, Scott J: 2 articles (10/2018 - 09/2011)
5.	Bartlett, Mitchell J: 1 article (10/2018)
6.	Flores, Andrew J: 1 article (10/2018)
7.	Heien, Michael L: 1 article (10/2018)
8.	Parent, Kate L: 1 article (10/2018)
9.	Root, Brandon K: 1 article (10/2018)
10.	Szabò, Lajos: 1 article (09/2011)

Related Diseases

1.	Dyskinesias (Dyskinesia) 10/01/2018 - "In this study, the mixed mu-delta agonist MMP-2200 was investigated in standard preclinical rodent models of PD and of LID to evaluate its effects on abnormal involuntary movements (AIMs). " 10/01/2018 - "The combination of the opioid glycopeptide MMP-2200 and a NMDA receptor antagonist reduced l-DOPA-induced dyskinesia and MMP-2200 by itself reduced dopamine receptor 2-like agonist-induced dyskinesia."
2.	Parkinsonian Disorders (Parkinsonism) 10/01/2018 - "In summary, the opioid glycopeptide MMP-2200 reduced AIMs induced by a D2R-like agonist, and MMP-2200 modified the effect of MK-801 to result in a potent reduction of l-DOPA-induced AIMs without induction of parkinsonism."
3.	Parkinson Disease (Parkinson's Disease) 09/21/2011 - "Effects of the novel glycopeptide opioid agonist MMP-2200 in preclinical models of Parkinson's disease."
4.	Hyperalgesia 09/01/2008 - "In an assay of capsaicin-induced thermal allodynia, both morphine (0.01-1.0 mg/kg) and MMP2200 (0.032-3.2 mg/kg) produced dose-dependent antiallodynic effects. "

Related Drugs and Biologics

1.	Glycopeptides
2.	Opioid Analgesics (Opioids)
3.	Dizocilpine Maleate (Dizocilpine)
4.	N-Methyl-D-Aspartate Receptors (NMDA Receptors)
5.	Dopamine Receptors (Dopamine Receptor)
6.	Morphine (MS Contin)
7.	Levodopa (L Dopa)
8.	Capsaicin (Zostrix)