Cutaneous anthrax

12/17/2012 - "When combined to protective antigen, GluPG immunization conferred full protection against cutaneous anthrax induced with a fully virulent strain."
01/01/2019 - "An ELISA using a recombinant chimera of protective antigen and lethal factor for serodiagnosis of cutaneous anthrax in India."
01/01/2016 - "Cutaneous anthrax promoted strong IFN-γ responses to all three antigens and antibody responses to PA and LF. "
08/01/2015 - "anthracis protective antigen (PA) in human cutaneous anthrax cases. "
11/01/2011 - "Lethal factor toxemia and anti-protective antigen antibody activity in naturally acquired cutaneous anthrax."

05/01/1994 - "A 41-year-old male patient was treated with penicillin for cutaneous anthrax affecting the region of the right eye. "
08/01/1948 - "Treatment of cutaneous anthrax with penicillin."
07/28/1945 - "Treatment of Human Cutaneous Anthrax with Penicillin."
06/02/1945 - "Cutaneous Anthrax treated with Penicillin."
05/01/2001 - "The latter symptoms - unusual for cutaneous anthrax - responded to intravenous penicillin therapy."

01/01/2015 - "Vaccines seeking to incorporate the robust, long-lasting, CD4 T cell immune responses observed in naturally acquired cutaneous anthrax cases may need to elicit a similarly broad spectrum cellular immune response."
03/01/2009 - "Nevertheless, vaccines that are effective against cutaneous anthrax may not be so against inhalational anthrax. "
05/01/2004 - "Recurrent, localized urticaria and erythema multiforme: a review and management of cutaneous anthrax vaccine-related events."
02/01/2006 - "The very lengthy and complicated dosing schedule of the current anthrax vaccine adsorbed, which was licensed in the USA for the prevention of cutaneous anthrax infection, calls for the development of an efficacious and easily administrable vaccine to prevent against the most lethal form of anthrax infection, the inhalation anthrax. "
09/20/2022 - "This was correlated with the binding affinities of epitopes to HLA class II molecules, as well as the responses of two human cohorts: individuals vaccinated with the Anthrax Vaccine Precipitated (AVP) vaccine (which contains PA and trace amounts of LF), and patients recovering from cutaneous anthrax infections. "

12/08/2001 - "Although naturally acquired cutaneous anthrax can be effectively treated with a short antibiotic cure, it is nevertheless advised in the USA to complete the full 60-day cure and to regard the cutaneous manifestation as a telltale sign of possible respiratory exposure. "
01/01/2012 - "Naturally occurring cutaneous anthrax: antibiotic treatment and outcome."
09/01/2007 - "In the event of clinical suspicion of cutaneous anthrax, the patient has to be treated by the recommended regimen of antibiotics because of the possibility of evolvution to an extensive or severe systemic disease, even in the absence of immuno-depressant factors."
02/20/2002 - "A 7-month-old infant with cutaneous anthrax developed severe systemic illness despite early treatment with antibiotics. "
01/01/2012 - "Cutaneous anthrax (CA) is the most common clinical presentation in human anthrax, but the duration of antibiotic therapy in naturally occurring CA is controversial. "

06/07/2002 - "The peak antibody level was observed 7-8 weeks after the onset of symptoms, and the time course and levels of detectable antibodies were consistent with those seen in other cases of cutaneous anthrax. "
02/01/2013 - "The assay could be a very useful tool for early diagnosis of cutaneous anthrax cases, as antibodies against LF appear much earlier than those against other anthrax toxins in human serum samples."
09/01/1992 - "Tests for antibodies against protective antigen and lethal factor using EIA and Western blot techniques were positive in three subjects (in paired sera) with cutaneous anthrax and in one subject who neither had had direct contact with the infected cow nor showed any sign of anthrax."

03/01/2009 - "Addition of formaldehyde-inactivated spores (FIS) to PA (PA-FIS) elicits total protection against cutaneous anthrax. "
06/01/2006 - "anthracis in formalin-fixed, paraffin-embedded tissue from bioterrorism-associated cases of inhalational and cutaneous anthrax and from a case of naturally occurring cutaneous anthrax. "

09/01/2016 - "The diagnosis of cutaneous anthrax was based on detailed history, dermatologic findings, including painless, ulcers covered by a characteristic black eschar and/or microbiological procedures, including Gram stain and culture of materials obtained from the lesions. "
03/01/2015 - "Cutaneous anthrax was diagnosed by the identification of typical anthrax lesions and/or the presence of Gram-positive-capsuled bacillus after staining with Gram stain and methylen blue in pathology samples obtained from these lesions and the presence of characteristic scarring with a history of severe swelling, black eschar, and positive response to treatment form the basis of diagnosis in cases where cultures were negative for the presence of bacillus. "

04/15/2009 - "One cluster-RCT provides limited evidence that a live-attenuated vaccine is effective in preventing cutaneous anthrax. "

09/15/2009 - "Treatment with penicillin G or penicillin procain alone is effective for cases with cutaneous anthrax without severe edema and superinfection."

10/01/2004 - "PA-specific IgG memory B cells were detectable in all 6 survivors of inhalation anthrax but in only 2 of 7 patients with cutaneous anthrax who were tested. "
10/01/2004 - "Anti-PA IgG remained detectable 8-16 months after the onset of symptoms in all 6 survivors of inhalation anthrax and in 7 of 11 survivors of cutaneous anthrax who were tested. "
09/01/2017 - "We aimed to evaluate clinical findings and risk factors of patients with cutaneous anthrax infection and report anti-lethal factor (LF) IgG and anti-protective antigen (PA) IgG titers in the serologic diagnosis of disease. "
09/01/2017 - "In this study, serum samples of 18 cutaneous anthrax patients were collected and anti-LF IgG and anti-PA IgG titers were measured by enzyme-linked immunosorbent assay (ELISA). "
02/01/2013 - "Serodiagnosis of human cutaneous anthrax in India using an indirect anti-lethal factor IgG enzyme-linked immunosorbent assay."

11/01/2010 - "The aim of this study was to evaluate the clinical findings, therapy, and outcome in children with cutaneous anthrax (CA). "
10/17/2022 - "In the Kyrgyz Republic, a country with endemic anthrax, cutaneous anthrax patients are routinely hospitalized and treated successfully with only monotherapy or dual therapy. "
05/01/2001 - "The latter symptoms - unusual for cutaneous anthrax - responded to intravenous penicillin therapy."
11/01/1972 - "Penicillin therapy of human cutaneous anthrax."
01/01/2012 - "Cutaneous anthrax (CA) is the most common clinical presentation in human anthrax, but the duration of antibiotic therapy in naturally occurring CA is controversial. "

01/01/1951 - "[Cutaneous anthrax treated with diathermy]."

08/14/2014 - "Sixteen of these presented as a severe soft tissue infection that differed clinically from cutaneous anthrax, lacked the characteristic epidemiological history of animal contact and ten cases required complimentary surgical debridement. "