HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

2-deoxy-2-fluorosorbitol

structure in first source

Also Known As:

(18)F-FDS

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Alcohols: 595
  - Sugar Alcohols: 143
    - Sorbitol: 1248
      - 2-deoxy-2-fluorosorbitol: 3
Carbohydrates: 22023
- Sugar Alcohols: 143
  - Sorbitol: 1248
    - 2-deoxy-2-fluorosorbitol: 3

Experts

1.	Wu, Zhanhong: 2 articles (03/2016 - 03/2008)
2.	Huo, Li: 1 article (03/2016)
3.	Li, Fang: 1 article (03/2016)
4.	Li, Zibo: 1 article (03/2016)
5.	Liu, Yimin: 1 article (03/2016)
6.	Ma, Yanru: 1 article (03/2016)
7.	Xing, Haiqun: 1 article (03/2016)
8.	Yao, Shaobo: 1 article (03/2016)
9.	Zhang, Yingqiang: 1 article (03/2016)
10.	Zhu, Wenjia: 1 article (03/2016)

Related Diseases

1.	Bacterial Infections (Bacterial Infection) 03/01/2016 - "We conclude that (18)F-FDS PET holds great potential for appropriate and effective for the imaging of bacterial infections in vivo. "
2.	Neoplasms (Cancer) 10/22/2014 - "In this report, we used commercially available 2-[(18)F]-fluorodeoxyglucose ((18)F-FDG) to produce 2-[(18)F]-fluorodeoxysorbitol ((18)F-FDS), a radioactive probe for Enterobacteriaceae, in 30 min. (18)F-FDS selectively accumulated in Enterobacteriaceae, but not in Gram-positive bacteria or healthy mammalian or cancer cells in vitro. " 03/01/2008 - "Despite the low accumulation in cell culture, (18)F-FDS had good tumor uptake and contrast in the subcutaneous U87MG tumor model (4.54%ID/g at 30 min post-injection). "
3.	Inflammation (Inflammations) 03/01/2008 - "(18)F-FDS also had increased uptake in the inflamed foci of the TPA-induced acute inflammation model. " 10/22/2014 - "In a murine myositis model, (18)F-FDS positron emission tomography (PET) rapidly differentiated true infection from sterile inflammation with a limit of detection of 6.2 ± 0.2 log10 colony-forming units (CFU) for Escherichia coli. "
4.	Infections 03/01/2016 - "The behavior of (18)F-FDS as an in vivo imaging probe for infections was evaluated in an Escherichia coli mouse infection model. " 03/01/2016 - "The recently reported (18)F-FDS ((18)F-2-fluorodeoxy sorbitol) as a PET (positron emission tomography) tracer can be used to image Enterobacteriaceae-specific infections and provides a potential alternative to this problem compared with other probes for imaging infections. " 03/01/2016 - "Infection Imaging With (18)F-FDS and First-in-Human Evaluation." 10/22/2014 - "Together, these data show that (18)F-FDS is a candidate imaging probe for translation to human clinical cases of known or suspected infections owing to Enterobacteriaceae. " 10/22/2014 - "In a murine myositis model, (18)F-FDS positron emission tomography (PET) rapidly differentiated true infection from sterile inflammation with a limit of detection of 6.2 ± 0.2 log10 colony-forming units (CFU) for Escherichia coli. "
5.	Myositis (Idiopathic Inflammatory Myopathies) 10/22/2014 - "In a murine myositis model, (18)F-FDS positron emission tomography (PET) rapidly differentiated true infection from sterile inflammation with a limit of detection of 6.2 ± 0.2 log10 colony-forming units (CFU) for Escherichia coli. "