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4- (8- fluoro- 2- oxo- 1,2- dihydroquinazolin- 3(4H)- yl)- N- (3- (7- methyl- 1H- indazol- 5- yl)- 1- oxo- 1- (4- (piperidin- 1- yl)piperidin- 1- yl)propan- 2- yl)piperidine- 1- carboxamide

structure in first source

Also Known As:

BMS 694153; BMS-694153; BMS694153

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - Indazoles: 179
        4-(8-fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinazolines: 402
      - Quinazolinones: 124
        4-(8-fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide: 2
    - Indazoles: 179
      - 4-(8-fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide: 2

Experts

1.	Conway, Charles M: 2 articles (04/2012 - 08/2008)
2.	Dubowchik, Gene M: 2 articles (04/2012 - 08/2008)
3.	Macor, John E: 2 articles (04/2012 - 08/2008)
4.	Pin, Sokhom S: 2 articles (04/2012 - 08/2008)
5.	Xu, Cen: 2 articles (04/2012 - 08/2008)
6.	Chen, Ling: 1 article (04/2012)
7.	Civiello, Rita: 1 article (04/2012)
8.	Kelley, Michelle: 1 article (04/2012)
9.	Kostich, Walter: 1 article (04/2012)
10.	Luo, Guanglin: 1 article (04/2012)

Related Diseases

1.

Migraine Disorders (Migraine)

08/28/2008 - "Discovery of (R)-4-(8-fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide (BMS-694153): a potent antagonist of the human calcitonin gene-related peptide receptor for migraine with rapid and efficient intranasal exposure."
04/15/2012 - "In our continuing efforts to identify CGRP receptor antagonists that can be dosed orally for the treatment of migraine headache, we have investigated a pyridine bioisosteric replacement of a polar amide portion of a previous lead compound, BMS-694153. "

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