1,2- bis(methylsulfonyl)- 1- (2- chloroethyl)hydrazine

a chloroethylating agent that alkylates and cross-links DNA; structure in first source

Also Known As:

90CE compound

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Penketh, Philip G: 1 article (06/2005)
2.	Rockwell, Sara: 1 article (06/2005)
3.	Sartorelli, Alan C: 1 article (06/2005)
4.	Seow, Helen A: 1 article (06/2005)
5.	Shyam, Krishnamurthy: 1 article (06/2005)

1.	Neoplasms (Cancer) 06/28/2005 - "To target malignant cells residing in hypoxic regions of solid tumors, we have designed and synthesized prodrugs generating the cytotoxic alkylating species 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)hydrazine (90CE) after bioreductive activation. "

1.	Prodrugs