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3- amino- 5,6,7,8- tetrahydro- 2- (4- (4- (quinolin- 2- yl)piperazin- 1- yl)butyl)quinazolin- 4- (3H)- one
Also Known As:
TZB 30878; TZB-30878; TZB30878
Networked:
1
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Quinazolines: 402
Quinazolinones: 124
3-amino-5,6,7,8-tetrahydro-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)butyl)quinazolin-4-(3H)-one: 1
Quinolines: 146
3-amino-5,6,7,8-tetrahydro-2-(4-(4-(quinolin-2-yl)piperazin-1-yl)butyl)quinazolin-4-(3H)-one: 1
Experts
1.
Asagarasu, Akira
: 1 article (09/2007)
2.
Nakano, Youichi
: 1 article (09/2007)
3.
Sakano, Sayuri
: 1 article (09/2007)
4.
Sato, Michitaka
: 1 article (09/2007)
5.
Tamaoki, Satoru
: 1 article (09/2007)
6.
Yamauchi, Yukinao
: 1 article (09/2007)
Related Diseases
1.
Irritable Bowel Syndrome (Syndrome, Irritable Bowel)
09/01/2007 - "
We hypothesized that TZB-30878 might have benefits from these dual effects as a medication for diarrhea-predominant irritable bowel syndrome (d-IBS), and these studies were designed to confirm the pharmacological properties of TZB-30878 and its efficacy in an IBS-like animal model.
"
2.
Diarrhea
09/01/2007 - "
We hypothesized that TZB-30878 might have benefits from these dual effects as a medication for diarrhea-predominant irritable bowel syndrome (d-IBS), and these studies were designed to confirm the pharmacological properties of TZB-30878 and its efficacy in an IBS-like animal model.
"
3.
Bradycardia
09/01/2007 - "
Systemic administration of TZB-30878 inhibited 5-HT-induced bradycardia in a dose-dependent manner in rats.
"