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spiruchostatin B

structure in first source

Also Known As:

(1S,7E,9S,13S,14R,19R)-14-sec-butyl-13-hydroxy-19-methyl-3,4-dithia-15,17,20-triazabicyclo(7.7.6)docos-7-ene-11,16,18,21-tetrone

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - Depsipeptides: 297
      - spiruchostatin B: 4
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - Depsipeptides: 297
      - spiruchostatin B: 4

Experts

1.	Katoh, Tadashi: 4 articles (06/2016 - 05/2012)
2.	Jawaid, Paras: 2 articles (06/2016 - 09/2014)
3.	Kondo, Takashi: 2 articles (06/2016 - 09/2014)
4.	Li, Peng: 2 articles (06/2016 - 09/2014)
5.	Narita, Koichi: 2 articles (06/2016 - 09/2014)
6.	Rehman, Mati Ur: 2 articles (06/2016 - 09/2014)
7.	Shimizu, Tadamichi: 2 articles (06/2016 - 09/2014)
8.	Zhao, Qing Li: 2 articles (06/2016 - 09/2014)
9.	Ishikawa, Masaaki: 2 articles (09/2012 - 05/2012)
10.	Kanno, Syu-Ichi: 2 articles (09/2012 - 05/2012)

Related Diseases

1.	Leukemia 09/01/2012 - "Characterization of cells resistant to the potent histone deacetylase inhibitor spiruchostatin B (SP-B) and effect of overexpressed p21waf1/cip1 on the SP-B resistance or susceptibility of human leukemia cells." 09/25/2014 - "Spiruchostatin A (SP-A) and spiruchostatin B (SP-B) are the potent histone deacetylase inhibitors (HDACi), that has the potential for chemotherapy of leukemia but the exact mechanism of these compounds remains unclear. " 05/01/2012 - "Spiruchostatin B (SP-B) is a potent histone deacetylase (HDAC) inhibitor that has potential for the chemotherapy of leukemia. " 09/01/2012 - "We previously showed that the B cell leukemia cell line NALM-6 had the highest susceptibility among a number of leukemia cell lines to spiruchostatin B (SP-B), a potent histone deacetylase (HDAC) inhibitor. "
2.	B-Cell Leukemia (Leukemia, B Cell) 05/01/2012 - "Involvement of p21waf1/cip1 expression in the cytotoxicity of the potent histone deacetylase inhibitor spiruchostatin B towards susceptible NALM-6 human B cell leukemia cells." 09/01/2012 - "We previously showed that the B cell leukemia cell line NALM-6 had the highest susceptibility among a number of leukemia cell lines to spiruchostatin B (SP-B), a potent histone deacetylase (HDAC) inhibitor. "
3.	Lymphoma (Lymphomas) 06/01/2016 - "Low-dose spiruchostatin-B, a potent histone deacetylase inhibitor enhances radiation-induced apoptosis in human lymphoma U937 cells via modulation of redox signaling."

Related Drugs and Biologics

1.	Histone Deacetylase Inhibitors
2.	Histone Deacetylases (Histone Deacetylase)
3.	spiruchostatin A

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)