Shao-Fu-Zhu-Yu

has constituent herbs with abundant volatile oil (Angelica sinensis, Ligusticum chuanxiong, Cinnamomum cassia, Foeniculum vulgare, Zingiber officinale); may inhibit oxytocin-induced uterine contraction; and reating primary dysmenorrhea

Also Known As:

Networked: 15 relevant articles (1 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Su, Shulan: 4 articles (06/2016 - 01/2010)
2.	Duan, Jin-Ao: 3 articles (06/2016 - 01/2010)
3.	Guo, Jianming: 3 articles (06/2016 - 02/2011)
4.	Shang, Erxin: 3 articles (06/2016 - 01/2010)
5.	Tang, Yuping: 3 articles (01/2013 - 01/2010)
6.	Cao, Ying: 2 articles (01/2020 - 01/2018)
7.	Jiang, Chunhua: 2 articles (01/2020 - 01/2018)
8.	Xu, Dingjie: 2 articles (01/2020 - 01/2018)
9.	Liu, Pei: 2 articles (06/2016 - 01/2013)
10.	Choi, Tae-Young: 2 articles (04/2016 - 01/2016)

Related Diseases

1.	Inflammation (Inflammations) 01/01/2017 - "Shaofu Zhuyu decoction ameliorates obesity-mediated hepatic steatosis and systemic inflammation by regulating metabolic pathways." 08/01/2018 - "According to the results, compared with the model group, Shaofu Zhuyu decoction could significantly improve the inflammation of the ectopic uterine cavity tissue, decrease the contents of TNF-α and IL-6 in the uterine cavity, the mRNA expressions of NK1 and GPER, and the protein expressions of MAPK and STAT1. " 12/01/2021 - "The targets such as interleukin 6(IL6) and prostaglandi-nendoperoxide synthase-2(PTGS2) were pivotal in the biological network of Shaofu Zhuyu Decoction intervention in EMT-induced dysmenorrhea, which involved multiple signaling pathways, including inflammation, hormones, and those promoted cell proliferation [e.g., mitogen-activated protein kinase(MAPK) and phosphatidylinositol-3 kinase(PI3 K)-protein kinase B(AKT)]. "
2.	Obesity 01/01/2017 - "Shaofu Zhuyu decoction ameliorates obesity-mediated hepatic steatosis and systemic inflammation by regulating metabolic pathways."
3.	Dysmenorrhea (Menstrual Pain) 12/01/2021 - "The findings of this study demonstrated that Shaofu Zhuyu Decoction could treat EMT-induced dysmenorrhea through multiple targets and multiple pathways, which could provide new ideas for investigating the underlying mechanism of Shaofu Zhuyu Decoction in the treatment of EMT-induced dysmenorrhea." 04/01/2016 - "Herbal medicine (Shaofu Zhuyu decoction) for treating primary dysmenorrhea: A systematic review of randomized clinical trials." 01/01/2010 - "The study also implied that Shaofu Zhuyu decoction may have direct inhibitory effects on the contractility of the mice uterus and justified the traditional use of the prescription for treating the uterine cramping associated dysmenorrhea." 12/01/2021 - "Additionally, there were 1 627 targets related to EMT and 142 targets related to dysmenorrhea with 107 common targets, and 42 potential therapeutic targets of Shaofu Zhuyu Decoction for the treatment of EMT-induced dysmenorrhea. " 12/01/2021 - "[Mechanism of Shaofu Zhuyu Decoction in treatment of EMT induced dysmenorrhea based on network pharmacology and molecular docking]."
4.	Endometriosis 01/01/2020 - "We previously showed that the Chinese herbal medicine, Shaofu Zhuyu decoction (SFZYD), shrank the size of endometriotic lesions in rats with endometriosis. " 08/01/2018 - "The aim of this paper is to study the molecular mechanism of Shaofu Zhuyu decoction in treating dysmenorrhea of endometriosis based on GPER2/MAPK/STAT1 axis. " 06/01/2023 - "[Shaofu Zhuyu Decoction attenuates fibrosis in endometriosis through regulating PTEN/Akt/mTOR signaling pathway]." 09/01/2022 - "[Mechanism of Shaofu Zhuyu Decoction in treatment of endometriosis-associated dysmenorrhea with syndrome of cold coagulation and blood stasis based on MSK1/2]." 08/01/2018 - "[Molecular mechanism of Shaofu Zhuyu decoction in treating endometriosis dysmenorrhea based on GPER2/MAPK/STAT1 axis]."
5.	Fibrosis (Cirrhosis) 06/01/2023 - "[Shaofu Zhuyu Decoction attenuates fibrosis in endometriosis through regulating PTEN/Akt/mTOR signaling pathway]." 06/01/2023 - "The present study aimed to investigate the protective role of Shaofu Zhuyu Decoction(SFZY) against endometriosis fibrosis in mice, and decipher the underlying mechanism through the phosphatase and tensin homolog deleted on chromosome ten(PTEN)/protein kinase B(Akt)/mammalian target of rapamycin(mTOR) pathway. "

Related Drugs and Biologics

1.	Phosphotransferases (Kinase)
2.	TOR Serine-Threonine Kinases
3.	PTEN Phosphohydrolase (PTEN Phosphatase)
4.	Therapeutic Uses
5.	Phosphoric Monoester Hydrolases (Phosphatases)
6.	Tensins
7.	mitogen and stress-activated protein kinase 1
8.	salicylhydroxamic acid (SHAM)
9.	Interleukin-6 (Interleukin 6)
10.	Messenger RNA (mRNA)

Related Therapies and Procedures

1.	Chinese Traditional Medicine (Traditional Chinese Medicine)
2.	Oral Administration