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(3,6- dimethyl- 2- (2,4,6- trimethylphenoxy)pyridin- 4- yl)(1- ethylpropyl)amine

a CRF1 receptor antagonist; structure in first source

Also Known As:

CP 376395; CP-376395; CP376395

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Aminopyridines: 77
    - (3,6-dimethyl-2-(2,4,6-trimethylphenoxy)pyridin-4-yl)(1-ethylpropyl)amine: 4
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Aminopyridines: 77
      - (3,6-dimethyl-2-(2,4,6-trimethylphenoxy)pyridin-4-yl)(1-ethylpropyl)amine: 4

Experts

1.	Benini, Ricardo: 2 articles (01/2021 - 07/2017)
2.	Crestani, Carlos C: 2 articles (01/2021 - 07/2017)
3.	Barretto-de-Souza, Lucas: 1 article (01/2021)
4.	Reis-Silva, Lilian L: 1 article (01/2021)
5.	Almeida, Jeferson: 1 article (07/2017)
6.	Gomes-de-Souza, Lucas: 1 article (07/2017)
7.	Oliveira, Leandro A: 1 article (07/2017)
8.	Bícego, Kênia Cardoso: 1 article (11/2016)
9.	Gargaglioni, Luciane H: 1 article (11/2016)
10.	Incheglu, Jolene M: 1 article (11/2016)

Related Diseases

1.	Tachycardia (Tachyarrhythmias) 07/01/2017 - "Bilateral microinjection of CP376395 into the BNST decreased the baroreflex bradycardiac response without affecting the reflex tachycardia. " 01/01/2021 - "However, the pharmacological approach did not indicate effect of the bilateral microinjection of either CP376395 or antisauvagine-30 into the LH in the tachycardia evoked by blood pressure decrease or the reflex bradycardia caused by blood pressure increase. "
2.	Hypersensitivity (Allergy) 06/01/2012 - "Infusion of CP376395 into the BNST(AL) inhibited somatic and colonic hypersensitivity in response to elevated amygdala CORT. "
3.	Hypercapnia 11/01/2016 - "Antalarmin (higher dose) and CP-376395 in the LC caused an increase in VE during normocapnia and hypercapnia, due to an increase in tidal volume. "
4.	Bradycardia 01/01/2021 - "However, the pharmacological approach did not indicate effect of the bilateral microinjection of either CP376395 or antisauvagine-30 into the LH in the tachycardia evoked by blood pressure decrease or the reflex bradycardia caused by blood pressure increase. "

Related Drugs and Biologics

1.	antisauvagine 30
2.	antalarmin