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10,11-dihydrodictyostatin

a potent analog of the marine anticancer agent dictyostatin; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Lactones: 1549
  - Macrolides: 4391
    - 10,11-dihydrodictyostatin: 1
  - Polyketides: 231
    - Macrolides: 4391
      - 10,11-dihydrodictyostatin: 1
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Polyketides: 231
    - Macrolides: 4391
      - 10,11-dihydrodictyostatin: 1

Experts

1.	Gardner, Nicola M: 1 article (03/2008)
2.	Paterson, Ian: 1 article (03/2008)
3.	Poullennec, Karine G: 1 article (03/2008)
4.	Wright, Amy E: 1 article (03/2008)

Related Diseases

1.	Neoplasms (Cancer) 03/01/2008 - "By employing a diverted total synthesis strategy with late-stage intermediates, 10,11-dihydrodictyostatin ( 5) was prepared and evaluated in vitro for growth inhibition against a range of human cancer cell lines, including the NCI/ADR Taxol-resistant cell line. "

Related Drugs and Biologics

1.	Paclitaxel (Taxol)