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monoclonal antibody 2G12

Subscribe to New Research on monoclonal antibody 2G12

an HIV-1 neutralizing agent in phase I clinical trials

Also Known As:

2G12 monoclonal antibody

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins
- Proteins: 90489
  - Blood Proteins: 4303
    - Serum Globulins: 75
      - Immunoglobulins: 23980
        Antibodies: 92632
        Monoclonal Antibodies: 18549
        monoclonal antibody 2G12: 2
    - Immunoproteins: 33
      - Immunoglobulins: 23980
        Antibodies: 92632
        Monoclonal Antibodies: 18549
        monoclonal antibody 2G12: 2
  - Globulins: 334
    - Serum Globulins: 75
      - Immunoglobulins: 23980
        Antibodies: 92632
        Monoclonal Antibodies: 18549
        monoclonal antibody 2G12: 2

Experts

1.	Husnain, Tayyab: 1 article (01/2013)
2.	Wadood, Abdul: 1 article (01/2013)
3.	Shah, Masaud: 1 article (01/2013)
4.	Rahman, Ziaur: 1 article (01/2013)
5.	Schols, Dominique: 1 article (05/2005)
6.	Froeyen, Matheus: 1 article (05/2005)
7.	De Clercq, Erik: 1 article (05/2005)
8.	Peumans, Willy: 1 article (05/2005)
9.	Bolmstedt, Anders: 1 article (05/2005)
10.	Van Damme, Els: 1 article (05/2005)

Related Diseases

1.	Infection 05/01/2005 - "They inhibit HIV-1 infection at a 50% effective concentration of 0.2 to 0.3 microg/ml. Escalating HHA or GNA concentrations (up to 500 microg/ml) led to the isolation of three HIV-1(III(B)) strains in CEM T cell cultures that were highly resistant to HHA and GNA, several other related mannose-specific plant lectins, and the monoclonal antibody 2G12, modestly resistant to the mannose-specific cyanovirin, which is derived from a blue-green alga, but fully susceptible to other HIV entry inhibitors as well as HIV reverse transcriptase inhibitors. "
2.	Dengue (Dengue Fever) 01/01/2013 - "Unrestrained pair wise docking was used for the interaction of dengue envelope protein with DC-SIGN and monoclonal antibody 2G12. "

Related Drugs and Biologics

1.	HIV Reverse Transcriptase
2.	Plant Lectins
3.	HIV Fusion Inhibitors
4.	Mannose (D-Mannose)
5.	DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)