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mouse NOX-E36-3'PEG

a Spiegelmer that binds Ccl2 and blocks recruitment of ex vivo-labeled macrophages to kidneys

Also Known As:

NOX-E36-3'PEG, mouse; mNOX-E36, pegylated; mNOX-E36-3'PEG; pegylated mNOX-E36

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Polynucleotides: 218
    - Oligonucleotides: 5145
      - Nucleotide Aptamers: 598
        mouse NOX-E36-3'PEG: 1

Experts

1.	Anders, Hans-Joachim: 1 article (03/2008)
2.	Buchner, Klaus: 1 article (03/2008)
3.	Clauss, Sebastian: 1 article (03/2008)
4.	Eulberg, Dirk: 1 article (03/2008)
5.	Klussmann, Sven: 1 article (03/2008)
6.	Kulkarni, Onkar: 1 article (03/2008)
7.	Ninichuk, Volha: 1 article (03/2008)
8.	Radomska, Ewa: 1 article (03/2008)
9.	Schmid, Holger: 1 article (03/2008)
10.	Segerer, Stephan: 1 article (03/2008)

Related Diseases

1.	Type 2 Diabetes Mellitus (MODY) 03/01/2008 - "We addressed this question by antagonizing Ccl2 with mNOX-E36-3'PEG, an anti-Ccl2 L-enantiomeric RNA aptamer (ie, a Spiegelmer), which binds murine Ccl2 and blocks the recruitment of ex vivo-labeled macrophages to the kidneys of db/db mice with type 2 diabetes. "

Related Drugs and Biologics

1.	Nucleotide Aptamers