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rat Cyb5R3 protein

Also Known As:

Cyb5R3 protein, rat; NADH-cytochrome b5 reductase 3; diaphorase 1; diaphorase-1; membrane-bound cytochrome b6 reductase, rat

Networked: 7 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - NADPH Oxidoreductases NADH
      - Cytochrome Reductases: 1
        Cytochrome-B(5) Reductase: 114
        rat Cyb5R3 protein: 7
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Flavoproteins: 234
    - Cytochrome-B(5) Reductase: 114
      - rat Cyb5R3 protein: 7

Experts

1.	Kedar, Prabhakar: 2 articles (01/2020 - 05/2017)
2.	Warang, Prashant: 2 articles (01/2020 - 05/2017)
3.	Chiddarwar, Ashish: 1 article (01/2020)
4.	Devendra, Rati: 1 article (01/2020)
5.	Gupta, Vinod: 1 article (01/2020)
6.	Kulkarni, Anuja: 1 article (01/2020)
7.	Colah, Roshan: 1 article (05/2017)
8.	Desai, Anand: 1 article (05/2017)
9.	Caterino, Tina Di: 1 article (11/2015)
10.	Ditzel, Henrik J: 1 article (11/2015)

Related Diseases

1.	Neoplasm Metastasis (Metastasis) 11/01/2015 - "NADH-Cytochrome b5 Reductase 3 Promotes Colonization and Metastasis Formation and Is a Prognostic Marker of Disease-Free and Overall Survival in Estrogen Receptor-Negative Breast Cancer."
2.	Breast Neoplasms (Breast Cancer) 11/01/2015 - "NADH-Cytochrome b5 Reductase 3 Promotes Colonization and Metastasis Formation and Is a Prognostic Marker of Disease-Free and Overall Survival in Estrogen Receptor-Negative Breast Cancer."
3.	Congenital Methemoglobinemia 01/01/2020 - "NADH-cytochrome b5 reductase 3 deficiency is an important genetic cause of recessive congenital methemoglobinemia (RCM) and occurs worldwide in autosomal recessive inheritance. " 04/15/2011 - "Congenital methemoglobinemia due to NADH-cytochrome b5 reductase 3 (CYB5R3) deficiency is an autosomal recessive disorder that occurs sporadically worldwide, although endemic clusters of this disorder have been identified in certain ethnic groups. " 05/01/2017 - "Congenital methemoglobinemia due to NADH-cytochrome b5 reductase 3 (CYB5R3) deficiencies is an autosomal recessive disorder that occurs sporadically worldwide, A sensitive, accurate, and rapid analysis of NADH-CYB5R enzyme concentrations is necessary for the diagnosis of RCM. " 04/01/2001 - "Molecular basis of recessive congenital methemoglobinemia, types I and II: Exon skipping and three novel missense mutations in the NADH-cytochrome b5 reductase (diaphorase 1) gene."
4.	Neoplasms (Cancer) 01/01/2009 - "Putative biomarkers such as cell cycle related genes (Cdc37), cancer cell adhesion (Glycam 1, integrin alpha8, integrin alphaX and Clec4n), signal transduction (Tlr2, IL-33, and Ccbp2), migration (Ccr1, Ccl6, and diaphorase 1 (Cyb5r3) and cancer development (epiregulin) can be useful for diagnosis and as prognosis markers and some of the target molecules can be applied for prevention of cancer." 11/01/2015 - "Using stable isotopic labeling by amino acids in cell culture and subcellular fractionation, the nuclear, cytosol, and mitochondria proteomes were analyzed by LC-MS/MS, identifying a number of proteins that exhibited altered expression in isogenic metastatic versus nonmetastatic cancer cell lines, including NADH-cytochrome b5 reductase 3 (CYB5R3), l-lactate dehydrogenase A (LDHA), Niemann-pick c1 protein (NPC1), and nucleolar RNA helicase 2 (NRH2). "
5.	Hemochromatosis (Bronze Diabetes) 02/01/2004 - "Four genes involved in iron homeostasis were included in the 50 differentially expressed genes [hemochromatosis (Hfe), diaphorase 1, transferrin receptor (Trfr) 2, and protoporphyrinogen oxidase] and two additional iron-related genes did not quite meet the stringent criteria for differential expression (Trfr and lactotransferrin). "

Related Drugs and Biologics

1.	Estrogen Receptors
2.	Epiregulin
3.	Protoporphyrinogen Oxidase (Protox)
4.	Cytochrome-B(5) Reductase (Methemoglobin Reductase)
5.	CD11c Antigen
6.	Proteome
7.	RNA Helicases (RNA Helicase)
8.	Biomarkers (Surrogate Marker)
9.	Transferrin Receptors (Transferrin Receptor)
10.	Proteins (Proteins, Gene)