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DMAG-N-oxide

a small molecule cell-impermeant Hsp90 antagonist that inhibits tumor cell motility and invasion

Also Known As:

dimethylaminoethylamino-17-demethoxygeldanamycin-N-oxide

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Lactams: 2198
    - Macrocyclic Lactams: 28
      - DMAG-N-oxide: 1
- Quinones: 434
  - Benzoquinones: 25
    - DMAG-N-oxide: 1
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Macrocyclic Lactams: 28
    - DMAG-N-oxide: 1

Experts

1.	Carreras, C: 1 article (04/2008)
2.	Felts, S: 1 article (04/2008)
3.	Koga, F: 1 article (04/2008)
4.	Lee, M-J: 1 article (04/2008)
5.	Neckers, L: 1 article (04/2008)
6.	Scroggins, B: 1 article (04/2008)
7.	Trepel, J: 1 article (04/2008)
8.	Tsutsumi, S: 1 article (04/2008)

Related Diseases

1.	Neoplasms (Cancer) 04/10/2008 - "We observed that, while not affecting intracellular Hsp90 function, DMAG-N-oxide significantly retarded tumor cell migration and integrin/extracellular matrix-dependent cytoskeletal reorganization. "

Related Drugs and Biologics

1.	Integrins