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(1S,2R)-2-hexyloxy carbonylamino-1 methyl-2-(3-methoxyphenyl) ethyl disodium phosphate

a tumor necrosis factor-alpha suppressant that prevents liver failure and promotes liver regeneration after extensive hepatectomy

Also Known As:

ONO-SM-362; ONO-SM362

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organophosphorus Compounds: 300
  - (1S,2R)-2-hexyloxy carbonylamino-1 methyl-2-(3-methoxyphenyl) ethyl disodium phosphate: 1

Experts

1.	Horiuchi, Hiroyuki: 1 article (04/2008)
2.	Ogata, Toshiro: 1 article (04/2008)
3.	Okuda, Koji: 1 article (04/2008)
4.	Todo, Satoru: 1 article (04/2008)
5.	Yamashita, Kenichiro: 1 article (04/2008)

Related Diseases

1.

04/01/2008 - "Suppression of excessive TNF-alpha production using ONO-SM362 ameliorated liver failure after 85% HTx."
04/01/2008 - "To test our hypothesis that modulation of endogenous TNF-alpha attenuates liver failure even after extensive HTx, we used ONO-SM362, a novel TNF-alpha inhibitor, in mice subjected to 85% HTx. "
04/01/2008 - "A novel tumor necrosis factor-alpha suppressant, ONO-SM362, prevents liver failure and promotes liver regeneration after extensive hepatectomy."

Related Drugs and Biologics

1.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)

Related Therapies and Procedures

1.	Hepatectomy