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crinine

structure in first source

Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Ethylamines: 5
    - Phenethylamines: 28
      - Amaryllidaceae Alkaloids: 33
        crinine: 4
Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Amaryllidaceae Alkaloids: 33
    - crinine: 4

Experts

1.	Evidente, Antonio: 2 articles (09/2016 - 05/2012)
2.	Kiss, Robert: 2 articles (09/2016 - 05/2012)
3.	Kornienko, Alexander: 2 articles (09/2016 - 05/2012)
4.	Lefranc, Florence: 2 articles (09/2016 - 05/2012)
5.	Magedov, Igor V: 2 articles (09/2016 - 05/2012)
6.	Mathieu, Véronique: 2 articles (09/2016 - 05/2012)
7.	Reisenauer, Mary R: 2 articles (09/2016 - 05/2012)
8.	Rogelj, Snezna: 2 articles (09/2016 - 05/2012)
9.	Behrendt, Torsten: 1 article (09/2022)
10.	Großmann, Luca M: 1 article (09/2022)

Related Diseases

1.	Neoplasms (Cancer) 09/14/2016 - "Using this discovery as a starting point and taking advantage of a concise biomimetic route to the crinine skeleton, a collection of crinine analogues were synthetically prepared and evaluated against cancer cells. " 05/01/2012 - "These, together with bulbispermine's natural crinine-type congeners, were evaluated in vitro against a panel of cancer cell lines with various levels of resistance to pro-apoptotic stimuli. " 05/01/2012 - "These findings lead us to argue that crinine-type alkaloids are potentially useful drug leads for the treatment of apoptosis-resistant cancers and glioblastoma in particular." 09/14/2016 - "Of these, crinine-type alkaloids based on the 5,10b-ethanophenanthridine ring system were recently shown to be effective at inhibiting proliferation of cancer cells resistant to various pro-apoptotic stimuli and representing tumors with dismal prognoses refractory to current chemotherapy, such as glioma, melanoma, non-small-cell lung, esophageal, head and neck cancers, among others. "
2.	Glioma (Gliomas) 05/01/2012 - "Bulbispermine: a crinine-type Amaryllidaceae alkaloid exhibiting cytostatic activity toward apoptosis-resistant glioma cells." 09/14/2016 - "Of these, crinine-type alkaloids based on the 5,10b-ethanophenanthridine ring system were recently shown to be effective at inhibiting proliferation of cancer cells resistant to various pro-apoptotic stimuli and representing tumors with dismal prognoses refractory to current chemotherapy, such as glioma, melanoma, non-small-cell lung, esophageal, head and neck cancers, among others. "
3.	Melanoma (Melanoma, Malignant) 09/14/2016 - "Of these, crinine-type alkaloids based on the 5,10b-ethanophenanthridine ring system were recently shown to be effective at inhibiting proliferation of cancer cells resistant to various pro-apoptotic stimuli and representing tumors with dismal prognoses refractory to current chemotherapy, such as glioma, melanoma, non-small-cell lung, esophageal, head and neck cancers, among others. "
4.	Head and Neck Neoplasms (Head and Neck Cancer) 09/14/2016 - "Of these, crinine-type alkaloids based on the 5,10b-ethanophenanthridine ring system were recently shown to be effective at inhibiting proliferation of cancer cells resistant to various pro-apoptotic stimuli and representing tumors with dismal prognoses refractory to current chemotherapy, such as glioma, melanoma, non-small-cell lung, esophageal, head and neck cancers, among others. "
5.	Glioblastoma (Glioblastoma Multiforme) 05/01/2012 - "These findings lead us to argue that crinine-type alkaloids are potentially useful drug leads for the treatment of apoptosis-resistant cancers and glioblastoma in particular."

Related Drugs and Biologics

1.	Alkaloids
2.	5,10b-ethanophenanthridine
3.	Cytostatic Agents
4.	Galantamine (Galanthamine)
5.	bulbispermine

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)