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2- methyl- 2- ((1- (3- phenyl- 7- propylbenzo(d)isoxazol- 6- yl)oxy)propyl)- 1H- 4- indolyloxypropanoic acid

structure in first source

Also Known As:

BPR1H0101

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - 2-methyl-2-((1-(3-phenyl-7-propylbenzo(d)isoxazol-6-yl)oxy)propyl)-1H-4-indolyloxypropanoic acid: 1
Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Propionates: 988
      - 2-methyl-2-((1-(3-phenyl-7-propylbenzo(d)isoxazol-6-yl)oxy)propyl)-1H-4-indolyloxypropanoic acid: 1
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Propionates: 988
      - 2-methyl-2-((1-(3-phenyl-7-propylbenzo(d)isoxazol-6-yl)oxy)propyl)-1H-4-indolyloxypropanoic acid: 1

Experts

1.	Chang, Jang-Yang: 1 article (02/2008)
2.	Chitlimalla, Santhosh Kumar: 1 article (02/2008)
3.	Chuang, Shuang-En: 1 article (02/2008)
4.	Hsieh, Hsing-Pang: 1 article (02/2008)
5.	Kao, Yu-Hsun: 1 article (02/2008)
6.	Kuo, Ching-Chuan: 1 article (02/2008)
7.	Lin, Wen-Hsing: 1 article (02/2008)
8.	Pan, Wen-Yu: 1 article (02/2008)
9.	Tsai, Yuan-Chin: 1 article (02/2008)

Related Diseases

1.	Mouth Neoplasms (Oral Cancer) 02/01/2008 - "A study of its mechanism showed that BPR1H0101 could inhibit the catalytic activity of topo II in vitro, but did not produce detectable topo II-mediated DNA strand breaks in human oral cancer KB cells. "
2.	Neoplasms (Cancer) 02/01/2008 - "A novel peroxisome proliferator-activated receptor alpha/gamma agonist, BPR1H0101, inhibits topoisomerase II catalytic activity in human cancer cells."
3.	Ataxia Telangiectasia (Louis Bar Syndrome) 02/01/2008 - "Furthermore, BPR1H0101 could inhibit VP16-induced topo II-mediated DNA cleavage and ataxia-telangiectasia-mutated phosphorylation in KB cells. "

Related Drugs and Biologics

1.	DNA (Deoxyribonucleic Acid)
2.	trioctyl phosphine oxide (TOPO)
3.	PPAR alpha
4.	Etoposide (VP 16)
5.	Type II DNA Topoisomerases (Topoisomerase II)