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exiguolide

a 16-membered macrolide isolated from the marine sponge Geodia exigua Thiele; structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Lactones: 1549
  - Macrolides: 4391
    - exiguolide: 2
  - Polyketides: 231
    - Macrolides: 4391
      - exiguolide: 2
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Polyketides: 231
    - Macrolides: 4391
      - exiguolide: 2

Experts

1.	Fuwa, Haruhiko: 2 articles (06/2013 - 02/2011)
2.	Kubo, Hiroshi: 2 articles (06/2013 - 02/2011)
3.	Sasaki, Makoto: 2 articles (06/2013 - 02/2011)
4.	Suzuki, Takaya: 2 articles (06/2013 - 02/2011)
5.	Mizunuma, Kana: 1 article (06/2013)
6.	Yamori, Takao: 1 article (02/2011)

Related Diseases

1.	Large Cell Carcinoma 06/07/2013 - "(-)-Exiguolide (1), isolated from the marine sponge Geodia exigua, has been shown to inhibit the growth of the A549 human lung adenocarcinoma and NCI-H460 human lung large cell carcinoma cells in vitro. " 02/25/2011 - "Assessment of the growth inhibitory activity of synthetic (-)-exiguolide against a panel of human cancer cell lines elucidated for the first time that this natural product is an effective antiproliferative agent against the NCI-H460 human lung large cell carcinoma and the A549 human lung adenocarcinoma cell lines. "
2.	Adenocarcinoma of Lung 06/07/2013 - "(-)-Exiguolide (1), isolated from the marine sponge Geodia exigua, has been shown to inhibit the growth of the A549 human lung adenocarcinoma and NCI-H460 human lung large cell carcinoma cells in vitro. " 02/25/2011 - "Assessment of the growth inhibitory activity of synthetic (-)-exiguolide against a panel of human cancer cell lines elucidated for the first time that this natural product is an effective antiproliferative agent against the NCI-H460 human lung large cell carcinoma and the A549 human lung adenocarcinoma cell lines. "
3.	Neoplasms (Cancer) 02/25/2011 - "Assessment of the growth inhibitory activity of synthetic (-)-exiguolide against a panel of human cancer cell lines elucidated for the first time that this natural product is an effective antiproliferative agent against the NCI-H460 human lung large cell carcinoma and the A549 human lung adenocarcinoma cell lines. "