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CH 4512600

structure in first source

Also Known As:

CH-4512600; CH4512600

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - CH 4512600: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzofurans: 26
      - CH 4512600: 1

Experts

1.	Hamada, Kenji: 1 article (01/2008)
2.	Kawai, Kenji: 1 article (01/2008)
3.	Kito, Chika: 1 article (01/2008)
4.	Miyazaki, Noriyuki: 1 article (01/2008)
5.	Monnai, Makoto: 1 article (01/2008)
6.	Nakamura, Masato: 1 article (01/2008)
7.	Nishime, Chiyoko: 1 article (01/2008)
8.	Ohnishi, Yasuyuki: 1 article (01/2008)
9.	Suemizu, Hiroshi: 1 article (01/2008)

Related Diseases

1.	Neoplasm Metastasis (Metastasis) 01/01/2008 - "We selected HCT 116 cell line from our liver metastasis model for evaluation of FTI CH4512600 efficacy in vivo. " 01/01/2008 - "Using the NOG mouse liver metastasis model, we demonstrated the effectiveness of FTI CH4512600 to suppress tumor growth in vivo and to prolong mouse survival significantly from 36.9+/-2.9 to 50.3+/-9.4 days." 01/01/2008 - "To examine the drug efficacy of a novel farnesyltransferase inhibitor (FTI), CH4512600, in vivo, we developed a reliable liver metastasis model of human colon cancer using NOD/Shi-scid IL2Rgamma(null) (NOG) mice. "
2.	Colonic Neoplasms (Colon Cancer) 01/01/2008 - "To examine the drug efficacy of a novel farnesyltransferase inhibitor (FTI), CH4512600, in vivo, we developed a reliable liver metastasis model of human colon cancer using NOD/Shi-scid IL2Rgamma(null) (NOG) mice. "
3.	Neoplasms (Cancer) 01/01/2008 - "Using the NOG mouse liver metastasis model, we demonstrated the effectiveness of FTI CH4512600 to suppress tumor growth in vivo and to prolong mouse survival significantly from 36.9+/-2.9 to 50.3+/-9.4 days."

Related Drugs and Biologics

1.	Farnesyltranstransferase (Farnesyltransferase)