phoxalone

isolated from the culture broth of a myxobacterium Sorangium cellulosum WXNXJ-C; structure in first source

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

1.	Neoplasms (Cancer) 12/01/2007 - "Study on the structure-activity relationships of phoxalone and induction of apoptosis in H446 tumor cells." 02/01/2008 - "Phoxalone, a novel macrolide from Sorangium cellulosum: structure identification and its anti-tumor bioactivity in vitro."
2.	Lung Neoplasms (Lung Cancer) 12/01/2007 - "The results of cytotoxic bioactivities on human non-small lung cancer H446, in vitro, showed that not only did phoxalone express higher antitumor bioactivity than many antitumor drugs, but it also displayed less cytotoxicity to normal human liver L02 cell lines (IC(50), 286 microg mL(-1)). "

1.	Macrolides
2.	Antineoplastic Agents (Antineoplastics)