HLA-DRB1*04

11/01/1999 - "Our study suggests that the estimation of HLA DRB1*04 allele subtypes serves as a marker for better identification of subjects at risk of IDDM development in the first degree relatives of IDDM patients."
06/01/1995 - "A previous study conducted on a group of diabetic Venezuelan families with IDDM proband demonstrated that the HLA-DRB1*04-DQA1*03-DQB1*0302 and DRB1*03-DQA1*0501-DQB1*0201 combinations present a strong association with susceptibility to IDDM. "
03/01/2000 - "In a separate case-control data set, we investigated the HLA-DRB1*04 and DQ allele distribution in 245 IDDM patients and 177 controls from Germany, all DR4 positive. "
03/01/2000 - "HLA-DRB1*04 and susceptibility to type 1 diabetes mellitus in a German/Belgian family and German case-control study. "
01/01/2000 - "Out of extensive genetic and epidemiological studies, the Caucasoid population is known to have a significant association of insulin-dependent diabetes mellitus with the increased frequencies of haplotypes HLA-DRB1*04-DQA1*0301-DQB1*0302 and DRB1*0301-DQA1*0501-DQB1*0201."

11/01/1997 - "Thus our findings, together with previous HLA studies on pemphigus vulgaris patients of different ethnic groups, suggest that HLA-DRB1*04 and DRB1*14 alleles are commonly associated with pemphigus vulgaris across racial barriers. "
04/01/2015 - "There is a strong association of HLA-DRB1*04 with pemphigus vulgaris in Pakistani population."
08/01/2011 - "HLA-DRB1*04:02, DRB1*08:04 and DRB1*14 alleles associated to pemphigus vulgaris in southeastern Brazilian population."
10/01/2003 - "A significant association between HLA-DRB1*04 (OR = 3.86; pcor = 0.0001) and DRB1*14 (OR = 8.4; pcor = 0.0001) and pemphigus vulgaris was found. "
11/01/1997 - "HLA-DRB1*04 and DRB1*14 alleles are associated with susceptibility to pemphigus among Japanese."

07/01/2001 - "Studies have shown an association between HLA-DRB1*04 and giant cell arteritis (GCA). "
07/01/2000 - "HLA-DRB1*04 may be a marker of severity in giant cell arteritis."

01/01/2013 - "Type 1 autoimmune pancreatitis (AIP) is characterized by a high serum IgG4 concentration and is closely associated with the HLA-DRB1(*)04:05-DQB1(*)04:01 haplotype, for which family studies may disclose its immunogenetic significance. "
01/01/2013 - "Contrary to our expectations, the siblings showed only normal or slightly elevated values of serum IgG4 and no HLA DRB1(*)04:05-DQB1(*)04:01 haplotype, suggesting that type 1 autoimmune pancreatitis is associated with multiple immunogenetic factors."

01/01/2012 - "Interaction between smoking and HLA-DRB1*04 gene is associated with a high cardiovascular risk in Brazilian Amazon patients with rheumatoid arthritis."
02/01/2007 - "The well-recognised susceptibility alleles to rheumatoid arthritis, HLA-DRB1*04, were associated with rheumatoid arthritis in Portuguese patients. "
11/11/2003 - "We propose that HLA-DRB1*04 alleles or genes in linkage disequilibrium regulate stem cell replication and contribute to the accumulation of senescent and autoreactive T cells in rheumatoid arthritis."
06/01/2003 - "Endothelium-dependent vasodilatation was lower in the 30 rheumatoid arthritis patients with the HLA-DRB1*04 shared epitope alleles (2.4% +/- 4.1%) than in the remaining patients (5.5% +/- 5.3%; P = 0.01). "
02/01/2002 - "Rheumatoid arthritis association in Colombian population is restricted to HLA-DRB1*04 QRRAA alleles."