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(2S,3R,4R)- 3- carboxymethyl- 4- (phenylthio)pyrrolidine- 2- carboxylic acid

a synthtic kainoid that serves as an anti-allodynic agent for neuropathic pain; structure in first source

Also Known As:

3-CPPC acid

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - Kainic Acid: 3549
      - (2S,3R,4R)-3-carboxymethyl-4-(phenylthio)pyrrolidine-2-carboxylic acid: 2

Experts

1.	Furuta, Kyoji: 2 articles (06/2013 - 12/2007)
2.	Ito, Seiji: 2 articles (06/2013 - 12/2007)
3.	Minami, Toshiaki: 2 articles (06/2013 - 12/2007)
4.	Suzuki, Masaaki: 2 articles (06/2013 - 12/2007)
5.	Doi, Hisashi: 1 article (06/2013)
6.	Kanazawa, Masakatsu: 1 article (06/2013)
7.	Lu, Jingshan: 1 article (06/2013)
8.	Matsumura, Shinji: 1 article (06/2013)
9.	Miyazaki, Shinichiro: 1 article (06/2013)
10.	Mizuma, Hiroshi: 1 article (06/2013)

Related Diseases

1.	Hyperalgesia 12/01/2007 - "In the present study we synthesized ACRO-A analogues (2S,3R,4R)-3-carboxymethyl-4-phenoxypyrrolidine-2-carboxylic acid (POPA-2) and (2S,3R,4R)-3-carboxymethyl-4-(phenylthio)pyrrolidine-2-carboxylic acid (PSPA-1) chemically and examined their ability to induce allodynia in conscious mice. " 06/15/2013 - "We previously demonstrated that intrathecal (i.t.) administration of acromelic acid A (Acro-A) induced allodynia in mice and that simultaneous administration of (2S,3R,4R)-3-carboxymethyl-4-(phenylthio)pyrrolidine-2-carboxylic acid (PSPA-1), an Acro-A analogue, attenuated the Acro-A-induced allodynia. "
2.	Neuralgia (Stump Neuralgia) 12/01/2007 - "A synthetic kainoid, (2S,3R,4R)-3-carboxymethyl-4-(phenylthio)pyrrolidine-2-carboxylic acid (PSPA-1) serves as a novel anti-allodynic agent for neuropathic pain."

Related Drugs and Biologics

1.	Acids
2.	acromelic acid A