Suramin

A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.

Also Known As:

Suramin Sodium; Germanin; Moranil; Naganin; Naganol; Naphuride; Suramin, Hexasodium Salt; Suramin, Monosodium Salt; Hexasodium Salt Suramin; Monosodium Salt Suramin; Salt Suramin, Hexasodium; Salt Suramin, Monosodium; Sodium, Suramin; 1,3,5-Naphthalenetrisulfonic acid, 8,8'- (carbonylbis(imino- 3,1- phenylenecarbonylimino(4- methyl- 3,1- phenylene)carbonylimino))bis-

Pharmalogical Action Categories:

Antinematodal Agents
Antineoplastic Agents
Trypanocidal Agents

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Naphthalenesulfonates: 2
        Suramin: 889
- Sulfur Compounds: 278
  - Sulfur Acids
    - Sulfonic Acids: 1605
      - Arylsulfonic Acids
        Arylsulfonates: 1
        Naphthalenesulfonates: 2
        Suramin: 889
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Naphthalenesulfonates: 2
      - Suramin: 889

NF157 compound

Bio-Agent Context: Research Results