punarnavine

11/25/2013 - "The present study sheds light on the potent anti-angiogenic of the punarnavine and can be extended further to develop therapeutic protocols for treatment of cancer."
11/25/2013 - "Punarnavine (15 mg/kg bw/d) treatment showed dose-dependent decrease in the ascitic fluid volume by 60.94% and tumor volume by 86.40% in Ehrlich ascites model. "
01/01/2009 - "Survival rate of the metastatic tumor-bearing animals were increased significantly by the administration of Punarnavine in all the modalities compared to the metastasis bearing untreated control. "
01/01/2007 - "The level and expression of TIMP-1 was also enhanced by the administration of Punarnavine compared to metastatic tumor bearing control. "
01/01/2007 - "Administration of Punarnavine enhanced Natural Killer (NK) cell activity, antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent complement mediated cytotoxicity (ACC) and the activity was observed in treated group much earlier compared to the metastatic tumor-bearing control. "

01/01/2009 - "These results indicate Punarnavine could inhibit the metastatic progression of B16F-10 melanoma cells in mice."
01/01/2007 - "These results indicate Punarnavine could enhance the immune response against metastatic progression of B16F-10 melanoma cells in mice."
01/01/2009 - "The objective of this study was to assess the effect of Punarnavine, an alkaloid isolated from Boerhaavia diffusa, on apoptosis in B16F-10 melanoma cells. "
01/01/2009 - "Punarnavine induces apoptosis in B16F-10 melanoma cells by inhibiting NF-kappaB signaling."
01/01/2009 - "Administration of Punarnavine (40mg/kg body weight) prophylactically (95.25%), simultaneously (93.9%) and 10 days after tumor inoculation (80.1%) could inhibit the metastatic colony formation of melanoma in lungs. "

01/01/2009 - "Survival rate of the metastatic tumor-bearing animals were increased significantly by the administration of Punarnavine in all the modalities compared to the metastasis bearing untreated control. "
08/01/2019 - "The present study was to find out whether punarnavine, the quinolizidine alkaloid, with already proven antimetastatic effect on spontaneous B16F10 pulmonary metastasis has got any effect on a drastic organ-specific breast cancer spread. "
01/01/2009 - "Punarnavine administration could suppress or down regulate the expression of MMP-2, MMP-9 (MMP--matrix metalloproteinase), ERK-1, ERK-2 (ERK--extracellular-signal-regulated kinase) and VEGF in the lung tissue of metastasis-induced animals. "

08/01/2019 - "The present study was to find out whether punarnavine, the quinolizidine alkaloid, with already proven antimetastatic effect on spontaneous B16F10 pulmonary metastasis has got any effect on a drastic organ-specific breast cancer spread. "

08/01/2019 - "The metastatic progression of 4T1 to lymph nodes, lungs, and liver was reduced by punarnavine (40 mg/kg body weight) administration in BALB/c mice. "
01/01/2009 - "Intraperitoneal administration of Punarnavine (40 mg/kg body weight) was found to enhance the total WBC count on 6(th) day. "
01/01/2009 - "Administration of Punarnavine (40mg/kg body weight) prophylactically (95.25%), simultaneously (93.9%) and 10 days after tumor inoculation (80.1%) could inhibit the metastatic colony formation of melanoma in lungs. "