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FV-100

antiviral; potent and selective inhibitors of varicella zoster virus; structure in first source
Also Known As:
3-(2-deoxy-b-D-ribofuranosyl)-6-(p-pentylphenyl)-2,3-dihydrofuro(2,3-d)pyrimidin-2-one, 50-valyl ester, HCl salt
Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. De Clercq, Erik: 2 articles (01/2022 - 09/2008)
2. Hill, Gordon T: 1 article (01/2017)
3. Lee, Patricia: 1 article (01/2017)
4. Matkovits, Theresa: 1 article (01/2017)
5. Moore, Angela Yen: 1 article (01/2017)
6. Silverfield, Joel C: 1 article (01/2017)
7. Sullivan-Bolyai, John: 1 article (01/2017)
8. Tyring, Stephen K: 1 article (01/2017)
9. Atiee, George: 1 article (06/2011)
10. Boehlecke, Brian: 1 article (06/2011)

Related Diseases

1. Herpes Zoster
2. Pain (Aches)
3. Neuralgia (Stump Neuralgia)
4. Infections
01/01/2022 - "FV-100 for the Treatment of Varicella-Virus (VZV) Infections: Quo Vadis?"
09/01/2008 - "Foremost among the newly described antiviral agents that may be developed into drugs are, for the treatment of human papilloma virus (HPV) infections, cPrPMEDAP; for the treatment of herpes simplex virus (HSV) infections, BAY 57-1293; for the treatment of varicella-zoster virus (VZV) infections, FV-100 (prodrug of Cf 1743); for the treatment of cytomegalovirus (CMV) infections, maribavir; for the treatment of poxvirus infections, ST-246; for the treatment of hepatitis B virus (HBV) infections, tenofovir disoproxil fumarate (TDF) (which in the meantime has already been approved in the EU); for the treatment of various DNA virus infections, the hexadecyloxypropyl (HDP) and octadecyloxyethyl (ODE) prodrugs of cidofovir; for the treatment of orthomyxovirus infections (i.e., influenza), peramivir; for the treatment of hepacivirus infections (i.e., hepatitis C), the protease inhibitors telaprevir and boceprevir, the nucleoside RNA replicase inhibitors (NRRIs) PSI-6130 and R1479, and various non-nucleoside RNA replicase inhibitors (NNRRIs); for the treatment of human immunodeficiency virus (HIV) infections, integrase inhibitors (INIs) such as elvitegravir, nucleoside reverse transcriptase inhibitors (NRTIs) such as apricitabine, non-nucleoside reverse transcriptase inhibitors (NNRTIs) such as rilpivirine and dapivirine; and for the treatment of both HCV and HIV infections, cyclosporin A derivatives such as the non-immunosuppressive Debio-025."
5. Postherpetic Neuralgia

Related Drugs and Biologics

1. Nucleosides
2. Antiviral Agents (Antivirals)
3. Prodrugs
4. Cf 1743
5. Integrase Inhibitors
6. Reverse Transcriptase Inhibitors
7. Cyclosporine (Ciclosporin)
8. RNA-Dependent RNA Polymerase (RNA Dependent RNA Polymerase)
9. Protease Inhibitors (Protease Inhibitor)
10. Valacyclovir (Valtrex)