HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

2- (4- (((2- (benzo(1,3)dioxol- 5- yloxy)- pyridine- 3- carbonyl)- amino)- methyl)- 3- fluoro- phenoxy)- propionic acid

structure in first source

Also Known As:

CP-671,305

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Propionates: 988
      - 2-(4-(((2-(benzo(1,3)dioxol-5-yloxy)-pyridine-3-carbonyl)-amino)-methyl)-3-fluoro-phenoxy)-propionic acid: 1
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Propionates: 988
      - 2-(4-(((2-(benzo(1,3)dioxol-5-yloxy)-pyridine-3-carbonyl)-amino)-methyl)-3-fluoro-phenoxy)-propionic acid: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - 2-(4-(((2-(benzo(1,3)dioxol-5-yloxy)-pyridine-3-carbonyl)-amino)-methyl)-3-fluoro-phenoxy)-propionic acid: 1

Experts

1.	Bi, Yi-An: 1 article (11/2007)
2.	Campbell, Scott D: 1 article (11/2007)
3.	Choo, Edna F: 1 article (11/2007)
4.	Davidson, Ralph E: 1 article (11/2007)
5.	Duignan, David B: 1 article (11/2007)
6.	Feng, Bo: 1 article (11/2007)
7.	Frederick, Kosea S: 1 article (11/2007)
8.	Hatch, Heather L: 1 article (11/2007)
9.	Kalgutkar, Amit S: 1 article (11/2007)
10.	Kazolias, Diana C: 1 article (11/2007)

Related Diseases

1.

Breast Neoplasms (Breast Cancer)

11/01/2007 - "Considering that cyclosporin A and rifampicin inhibit multiple uptake/efflux transporters, the interactions of CP-671,305 with major human hepatic drug transporters, multidrug resistance protein 1 (MDR1), multidrug resistance-associated protein 2 (MRP2), breast cancer resistant protein (BCRP), and organic anion-transporting polypeptide (OATPs) were evaluated in vitro. "

Related Drugs and Biologics

1.	Member 1 Subfamily B ATP Binding Cassette Transporter
2.	Cyclosporine (Ciclosporin)
3.	Rifampin (Rifampicin)
4.	Proteins (Proteins, Gene)
5.	Peptides (Polypeptides)
6.	Anions
7.	Multidrug Resistance-Associated Protein 2