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JK184

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structure in first source

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 60
- 1-Ring Heterocyclic Compounds
  - Azoles: 413
    - Thiazoles: 23
      - JK184: 1
- 2-Ring Heterocyclic Compounds
  - JK184: 1
Organic Chemicals: 58
- Sulfur Compounds: 135
  - Thiazoles: 23
    - JK184: 1

Experts

1.	Wu, Qinjie: 1 article (02/2015)
2.	Wei, Yuquan: 1 article (02/2015)
3.	Liu, Shichang: 1 article (02/2015)
4.	Liu, Lei: 1 article (02/2015)
5.	Xie, Yongmei: 1 article (02/2015)
6.	Gong, Changyang: 1 article (02/2015)
7.	Deng, Senyi: 1 article (02/2015)
8.	Zhang, Nannan: 1 article (02/2015)
9.	Su, Weijun: 1 article (02/2015)
10.	Wang, Ning: 1 article (02/2015)

Related Diseases

1.	Neoplasms (Cancer) 02/14/2015 - "JK184 can specially inhibit Gli in the Hedgehog (Hh) pathway, which showed great promise for cancer therapeutics. " 02/14/2015 - "Our results suggested that JK184 micelles are a promising drug candidate for treating pancreatic tumors with a highly inhibitory effect on Hh activity. " 02/14/2015 - "Furthermore, JK184 micelles had stronger tumor growth inhibiting effects in subcutaneous Panc-1 and BxPC-3 tumor models. " 02/14/2015 - "JK184 micelles induced more apoptosis and blocked proliferation of Panc-1 and BxPC-3 tumor cells. " 02/14/2015 - "Biodegradable polymeric micelles encapsulated JK184 suppress tumor growth through inhibiting Hedgehog signaling pathway."
2.	Carcinoma (Carcinomatosis) 02/14/2015 - "JK184 micelles showed a stronger inhibition of Gli expression in Hh signaling, which played an important role in pancreatic carcinoma. "

Related Drugs and Biologics

1.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
2.	Micelles
3.	Surface-Active Agents (Surfactants)
4.	Solvents
5.	monomethoxypolyethylene glycol (MPEG)

Related Therapies and Procedures

1.	Therapeutics