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mouse metallothionein-1

GenBank AK018727

Also Known As:

metallothionein-1, mouse; MT-1 protein, mouse

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Metalloproteins: 164
    - Metallothionein: 1832
      - mouse metallothionein-1: 5

Experts

1.	Atrian, Silvia: 1 article (01/2019)
2.	Capdevila, Mercè: 1 article (01/2019)
3.	Comes, Gemma: 1 article (01/2019)
4.	Fernandez-Gayol, Olaya: 1 article (01/2019)
5.	Giralt, Mercedes: 1 article (01/2019)
6.	Hidalgo, Juan: 1 article (01/2019)
7.	Molinero, Amalia: 1 article (01/2019)
8.	Anthony, D D: 1 article (03/2000)
9.	Guo, Y: 1 article (03/2000)
10.	Habib, N: 1 article (03/2000)

Related Diseases

1.	Glioma (Gliomas) 07/01/1997 - "Replacement of the RSV-LTR promoter with the heavy metal-inducible mouse metallothionein-1 promoter in the lacR-responsive unit, as well as the generation of a clonal glioma cell line expressing lacR, did not significantly enhance regulation of DTA in the Lac system. " 01/14/1994 - "Transient expression analyses, however, indicate that this sequence, which contains a core heptanucleotide, TGCACTC, identical to that of the strongest metal regulatory element of the mouse metallothionein-1 gene, is not responsive to Cd2+ or Zn2+. Stable transfection of constructs containing the entire mouse HO-1 gene and various portions of the 5'-flanking region into rat C6 glioma cells and simultaneous, quantitative analysis of the mouse and rat HO-1 mRNAs indicate that distal 5' sequences, between positions -3.5 and -12.5 kbp, are required for induction of mouse HO-1 gene transcription by both heme and heavy metals. "
2.	Testicular Neoplasms (Testicular Cancer) 03/07/1996 - "MT-PVLT-10 transgenic mice express large T-antigen of polyomavirus under the control of the mouse metallothionein-1 promoter and mates of this transgenic line develop testicular tumors at advanced ages. "
3.	Neoplasms (Cancer) 03/01/2000 - "Tumor cells transfected with a vector encoding an IGF-1 antisense cDNA transcriptional cassette driven by the mouse metallothionein-1 promoter become immunogenic and lose their tumorigenicity in syngeneic animals. "
4.	Multiple Sclerosis 01/01/2019 - "Mouse metallothionein-1 and metallothionein-2 are not biologically interchangeable in an animal model of multiple sclerosis, EAE."

Related Drugs and Biologics

1.	Heavy Metals
2.	Complementary DNA (cDNA)
3.	Metals
4.	Insulin-Like Growth Factor I (IGF-1)
5.	Heme (Haem)
6.	Elements
7.	Tumor Viral Antigens (Large T Antigen)