guizhi-fuling

a traditional Chinese medical (Kampo) formulation composed of five kinds of medicinal plants, Cinnamomum cassia BLUME (Cinnamomi Cortex), Paeonia lactiflora PALL. (Peonies Radix), Paeonia suffruticosa ANDREWS (Moutan Cortex), Prunus persica BATSCH (Persicae Semen), and Poria cocos WOLF (Hoelen); may be beneficial for the treatment of brain ischemia-reperfusion injury partly due to its anti-inflammatory properties

Also Known As:

Networked: 62 relevant articles (6 outcomes, 16 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Xiao, Wei: 18 articles (06/2021 - 10/2012)
2.	Ding, Gang: 7 articles (09/2016 - 03/2015)
3.	Wang, Zhen-zhong: 7 articles (06/2015 - 11/2014)
4.	Cao, Liang: 6 articles (01/2021 - 03/2015)
5.	Li, Na: 6 articles (06/2015 - 03/2015)
6.	Wang, Zhenzhong: 5 articles (01/2021 - 09/2017)
7.	Zhang, Yu: 3 articles (01/2021 - 09/2017)
8.	Zhao, Longshan: 3 articles (09/2018 - 09/2017)
9.	Wang, Zhen-Zhong: 3 articles (01/2016 - 10/2012)
10.	Wang, Tuan-jie: 3 articles (03/2015 - 03/2015)

Related Diseases

1.	Dysmenorrhea (Menstrual Pain) 01/01/2021 - "Metabolomics Study of Guizhi Fuling Capsules in Rats With Cold Coagulation Dysmenorrhea." 01/01/2020 - "Guizhi Fuling was first prescribed by Zhang Zhongjing almost two thousand years ago for the treatment of primary dysmenorrhea. " 01/01/2022 - "Guizhi Fuling pill (GZFL), a modern preparation from traditional Chinese medicine, exhibited anti-dysmenorrhea, anti-inflammatory, and immune-regulative effects. " 01/01/2021 - "Guizhi Fuling Capsules are mainly used for the treatment of various pain syndromes and especially effective in treating primary dysmenorrhea. " 03/01/2015 - "In this study, the active components and potential molecular .mechanism of Guizhi Fuling formula in treatment on dysmenorrhea, pelvic inflammation, and hysteromyoma were investigated using network pharmacological methods. "
2.	Pain (Aches) 06/01/2013 - "Guizhi Fuling significantly reduces the pain duration compared to placebo and high-dose is better than low-dose. " 01/01/2021 - "Guizhi Fuling Capsules are mainly used for the treatment of various pain syndromes and especially effective in treating primary dysmenorrhea. " 10/28/2022 - "Systemic pharmacological verification of Guizhi Fuling decoction in treating endometriosis-associated pain." 06/01/2013 - "Guizhi Fuling capsule at high or low dose significantly relieves the pain, improves symptoms, reduces the duration of pain, and has a better overall treatment effect and long-term treatment effect in patients with primary dysmenorrhea." 01/01/2016 - "Guizhi Fuling capsule (GZFL), a traditional Chinese medicine formulation, is widely used in China to relieve pain from dysmenorrhea and is now in a Phase II clinical trial in the USA. "
3.	Endometrial Hyperplasia 01/01/2021 - "Pathological sections of uterus and ovaries also showed that Guizhi Fuling Capsules could significantly relieve endometrial hyperplasia and improve ovarian function. " 06/28/2021 - "Guizhi Fuling Capsule ameliorates endometrial hyperplasia through promoting p62-Keap1-NRF2-mediated ferroptosis."
4.	Brain Ischemia (Cerebral Ischemia) 09/01/1998 - "To Probe the action of the Chinese traditional medicine Guizhi Fuling Pills on rats with cerebral ischemia and reirrigation. " 09/01/2007 - "Protective effects of Guizhi-Fuling-Capsules on rat brain ischemia/reperfusion injury." 09/01/1998 - "[Effect of guizhi fuling pills on the changes of Ca2+ and amino acids in rats with cerebral ischemia and reperfusion]."
5.	Myocardial Ischemia (Ischemic Heart Diseases) 10/01/2022 - "Guizhi-Fuling (GZFL) is effective in treating Myocardial ischemia. " 10/01/2022 - "Integrated Metabolomics and Network Pharmacology to Reveal the Mechanisms of Guizhi-Fuling Treatment for Myocardial Ischemia."

Related Drugs and Biologics

1.	Capsules (Microcapsules)
2.	Mifepristone (RU 486)
3.	Carbon Tetrachloride (Tetrachloromethane)
4.	Nonprescription Drugs (Patent Medicines)
5.	Facilitative Glucose Transport Proteins (Glucose Transporter)
6.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
7.	Messenger RNA (mRNA)
8.	Analgesics (Analgesic Drugs)
9.	paeonol
10.	Estradiol (Delestrogen)

Related Therapies and Procedures

1.	Chinese Traditional Medicine (Traditional Chinese Medicine)
2.	Therapeutics
3.	Traditional Medicine (Folk Remedies)