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2'- fluoro- 6,7- methylenedioxy- 2- phenyl- 4- quinolone

structure in first source

Also Known As:

CHM-1 compound

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Dioxoles
    - 2'-fluoro-6,7-methylenedioxy-2-phenyl-4-quinolone: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Quinolones: 2938
        2'-fluoro-6,7-methylenedioxy-2-phenyl-4-quinolone: 2

Experts

1.	Chen, Shih-Shun: 1 article (10/2015)
2.	Lin, Meng-Liang: 1 article (10/2015)
3.	Ng, Sue-Hwee: 1 article (10/2015)
4.	Chiang, Po-Cheng: 1 article (02/2008)
5.	Guh, Jih-Hwa: 1 article (02/2008)
6.	Huang, Der-Yi: 1 article (02/2008)
7.	Huang, Yu-Chun: 1 article (02/2008)
8.	Kuo, Sheng-Chu: 1 article (02/2008)
9.	Lee, Kuo-Hsiung: 1 article (02/2008)
10.	Pan, Shiow-Lin: 1 article (02/2008)

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 02/01/2008 - "In this study, 2'-fluoro-6,7-methylenedioxy-2-phenyl-4-quinolone (CHM-1), a synthetic 6,7-substituted 2-phenyl-4-quinolone, was identified as a potent and selective antitumor agent in human hepatocellular carcinoma. "
2.	Nasopharyngeal Carcinoma 10/01/2015 - "Hereιin we report that 2'-fluoro-6,7-methylenedioxy-2-phenyl-4-quinolone (CHM-1) induces apoptosis of human nasopharyngeal carcinoma (NPC) cells, as characterized by morphological changes, DNA fragmentation, caspase-3 activation, and cleavage of poly (ADP-ribose) polymerase. "

Related Drugs and Biologics

1.	Antineoplastic Agents (Antineoplastics)
2.	2-phenyl-4-oxohydroquinoline
3.	Caspase 3 (Caspase-3)
4.	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)