EMD478761

a nonpeptide diastereomer benzoxazinone; an alpha(v)beta(3)/alpha(v)beta(5) integrin antagonist

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Drug-Related Side Effects and Adverse Reactions 11/01/2007 - "Sustained delivery of EMD478761 significantly inhibited bFGF-induced angiogenesis in CAM, as determined by a reduction in angiogenesis areas, without drug toxicity to the normal CAM vasculature. "
2.	Choroidal Neovascularization 11/01/2007 - "Angiogenesis inhibition and choroidal neovascularization suppression by sustained delivery of an integrin antagonist, EMD478761." 11/01/2007 - "To evaluate the angiogenic inhibitory effects of an alpha(v)beta(3)/alpha(v)beta(5) integrin antagonist, EMD478761, released from a polymeric implant in a chick chorioallantoic membrane (CAM) assay and laser-induced experimental choroidal neovascularization (CNV) in rats. "

1.	Lasers (Laser)