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benzyl-DTPA

structure in first source

Also Known As:

benzyl-diethylenetriamine pentaacetic acid

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Polyamines: 3918
    - Pentetic Acid: 1751
      - benzyl-DTPA: 6
- Carboxylic Acids: 973
  - Acyclic Acids
    - Acetates: 4994
      - Pentetic Acid: 1751
        benzyl-DTPA: 6

Experts

1.	Orlova, Anna: 2 articles (09/2007 - 08/2003)
2.	Tolmachev, Vladimir: 2 articles (09/2007 - 08/2003)
3.	Akahane, Masaaki: 1 article (10/2012)
4.	Akai, Hiroyuki: 1 article (10/2012)
5.	Imamura, Hiroshi: 1 article (10/2012)
6.	Kiryu, Shigeru: 1 article (10/2012)
7.	Kokudo, Norihiro: 1 article (10/2012)
8.	Ohtomo, Kuni: 1 article (10/2012)
9.	Tajima, Taku: 1 article (10/2012)
10.	Takao, Hidemasa: 1 article (10/2012)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 07/01/1993 - "Radioimmunolocalization of metastatic breast carcinoma using indium-111-methyl benzyl DTPA BrE-3 monoclonal antibody: phase I study."
2.	Neoplasms (Cancer) 09/01/2007 - "The use of benzyl-DTPA provided higher tumor-to-blood and tumor-to-liver ratios. " 11/01/1998 - "The retention of [90Y]DOTA-hLL2 on Raji tumor cells in vitro was similar to that of the same mAb labeled with [90Y]benzyl-DTPA and was about twice as much as with [125I]hLL2, indicating residualization of metalated mAb. Both [90Y]hLL2 conjugates, prepared using DOTA and Bz-DTPA, had similar maximum tolerated doses of 125 muCi in BALB/c mice and showed no discernible chelator-induced immune responses. "
3.	Ovarian Neoplasms (Ovarian Cancer) 08/01/1992 - "Monoclonal antibody 2G3 directed against a high molecular weight glycoprotein on breast and ovarian cancer cells was conjugated with bicyclic DTPA (or EDTA) anhydride or benzyl isothiocyanate DTPA (benzyl DTPA) and labeled with 111In. "
4.	Neoplasm Metastasis (Metastasis) 10/01/2012 - "We compared diagnostic ability for detecting hepatic metastases between gadolinium ethoxy benzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) on a 1.5-T system, and determined whether DWI is necessary in Gd-EOB-DTPA-enhanced MRI for diagnosing colorectal liver metastases. "
5.	Glioma (Gliomas) 08/01/2003 - "The obtained [(111)In]benzyl-DTPA-hEGF conjugate was characterized in vitro using the EGFR expressing glioma cell line U343MGaCl2:6. The binding affinity, internalization, and retention of the conjugate were studied. "

Related Drugs and Biologics

1.	Monoclonal Antibodies
2.	Pentetic Acid (DTPA)
3.	Glycoproteins (Glycoprotein)
4.	Gadolinium
5.	Edetic Acid (EDTA)
6.	Chelating Agents
7.	Anhydrides
8.	epratuzumab
9.	gadolinium ethoxybenzyl DTPA
10.	1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid