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(S)-4-(1-(5-chloro-2-(4-fluorophenyoxy) benzamido)ethyl) benzoic acid

Subscribe to New Research on (S)-4-(1-(5-chloro-2-(4-fluorophenyoxy) benzamido)ethyl) benzoic acid

a selective antagonist of prostaglandin E receptor subtype 4

Also Known As:

CJ-42794

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 58
- Amides: 231
  - Benzamides: 80
    - (S)-4-(1-(5-chloro-2-(4-fluorophenyoxy) benzamido)ethyl) benzoic acid: 2
- Carboxylic Acids: 83
  - Carbocyclic Acids
    - Benzoic Acids: 18
      - Benzamides: 80
        (S)-4-(1-(5-chloro-2-(4-fluorophenyoxy) benzamido)ethyl) benzoic acid: 2

Experts

1.	Amagase, Kikuko: 2 articles (10/2007 - 09/2007)
2.	Kato, Shinichi: 2 articles (10/2007 - 09/2007)
3.	Takeuchi, Koji: 2 articles (10/2007 - 09/2007)
4.	Tanaka, Akiko: 2 articles (10/2007 - 09/2007)
5.	Hatazawa, Ryo: 1 article (10/2007)
6.	Ashida, Yasuko: 1 article (10/2007)
7.	Tanigami, Mayu: 1 article (10/2007)
8.	Aihara, Eitaro: 1 article (09/2007)

Related Diseases

1.	Ulcer 10/01/2007 - "By contrast, CJ-42794 (selective EP(4) antagonist) significantly delayed the ulcer healing in rats and mice. "
2.	Stomach Ulcer (Gastric Ulcer) 09/01/2007 - "These results suggest that CJ-42794 does not cause any damage in the normal rat gastrointestinal mucosa and in the arthritic rat stomach and does not worsen the gastric ulcerogenic response to stress or aspirin in normal rats, although this agent slightly damages the small intestine of arthritic rats and impairs the healing of gastric ulcers." 09/01/2007 - "The repeated administration of CJ-42794 and rofecoxib as well as indomethacin impaired the healing of chronic gastric ulcers with a down-regulation of vascular endothelial growth factor expression in the ulcerated mucosa. "

Related Drugs and Biologics

1.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
2.	Indomethacin (Indometacin)
3.	Aspirin (Acetylsalicylic Acid)
4.	rofecoxib (Vioxx)