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SR 13668

has antineoplastic activity; structure in first source

Also Known As:

SR-13668; SR13668

Networked: 8 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Carbazoles: 32
        SR 13668: 8
  - 3-Ring Heterocyclic Compounds
    - Carbazoles: 32
      - SR 13668: 8

Experts

1.	Kapetanovic, Izet M: 5 articles (01/2013 - 05/2009)
2.	Jong, Ling: 4 articles (05/2011 - 07/2007)
3.	Banerjee, Aryamitra A: 2 articles (01/2013 - 10/2012)
4.	Hautman, Mathew: 2 articles (01/2013 - 10/2012)
5.	Hong, Seungpyo: 2 articles (01/2013 - 10/2012)
6.	Liu, Ying: 2 articles (01/2013 - 10/2012)
7.	Lyubimov, Alexander V: 2 articles (01/2013 - 10/2012)
8.	Shen, Hao: 2 articles (01/2013 - 10/2012)
9.	Haslam, John L: 2 articles (03/2011 - 05/2010)
10.	Rajewski, Roger A: 2 articles (03/2011 - 05/2010)

Related Diseases

1.

Neoplasms (Cancer)

05/01/2011 - "Improved oral bioavailability in rats of SR13668, a novel anti-cancer agent."
03/01/2011 - "SR13668, an orally active Akt pathway inhibitor, has demonstrated cancer chemopreventive potential in preclinical studies. "
01/01/2013 - "Potency and activity of SR13668 in cancer prevention have been proven in several in vitro and in vivo cancer models. "
10/01/2012 - "Enhanced oral bioavailability of a cancer preventive agent (SR13668) by employing polymeric nanoparticles with high drug loading."
05/01/2010 - "SR13668 (2,10-dicarbethoxy-6-methoxy-5,7-dihydro-indolo-(2,3-b)carbazole), is a new candidate cancer chemopreventive agent under development. "

Related Drugs and Biologics

1.	carbazole
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5.	Peroxisome Proliferator-Activated Receptors (PPAR)
6.	Cyclins
7.	Synthetic Drugs