N- (4- (4- amino- 2- ethyl- 1H- imidazo(4,5c)quinolin- 1- yl)butyl)methanesulfonamide

structure in first source

Also Known As:

852A compound; N-(4-(4-amino-2-ethyl-1H-imidazo(4,5-c)quinolin-1-yl)butyl)methanesulfonamide; PF-04878691; S 32865; S-32865; S32865; toll-like receptor 7 agonist 852A

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - N-(4-(4-amino-2-ethyl-1H-imidazo(4,5c)quinolin-1-yl)butyl)methanesulfonamide: 2
Organic Chemicals: 133
- Amides: 2428
  - Sulfonamides: 2809
    - N-(4-(4-amino-2-ethyl-1H-imidazo(4,5c)quinolin-1-yl)butyl)methanesulfonamide: 2
- Sulfur Compounds: 278
  - Sulfones: 534
    - Sulfonamides: 2809
      - N-(4-(4-amino-2-ethyl-1H-imidazo(4,5c)quinolin-1-yl)butyl)methanesulfonamide: 2

Experts

1.	Chan, Phylinda L S: 1 article (01/2012)
2.	Jones, Hannah M: 1 article (01/2012)
3.	Webster, Robert: 1 article (01/2012)
4.	van der Graaf, Piet H: 1 article (01/2012)
5.	Cooley, Sarah: 1 article (12/2007)
6.	Dudek, Arkadiusz Z: 1 article (12/2007)
7.	Gorski, Kevin S: 1 article (12/2007)
8.	Harrison, Lester I: 1 article (12/2007)
9.	Hawkinson, Ronald: 1 article (12/2007)
10.	Kumar, Sandeep: 1 article (12/2007)

Related Diseases

1.	Chronic Hepatitis C 01/01/2012 - "To use non-linear mixed effects modelling and simulation techniques to predict whether PF-04878691, a toll-like receptor 7 (TLR7) agonist, would produce sufficient antiviral efficacy while maintaining an acceptable side effect profile in a 'proof of concept' (POC) study in chronic hepatitis C (HCV) patients. "
2.	Neoplasms (Cancer) 12/01/2007 - "We studied the systemic administration of the Toll-like receptor 7 agonist 852A, a small-molecule imidazoquinoline, in patients with advanced cancer. "
3.	Hepatitis C 01/01/2012 - "Use of modelling and simulation techniques to support decision making on the progression of PF-04878691, a TLR7 agonist being developed for hepatitis C."

Related Drugs and Biologics

1.	Toll-Like Receptor 7
2.	Antiviral Agents (Antivirals)