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malabaricone A

from Myristica malabarica (rampatri), has antipromastigote activity; structure in first source

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        Resorcinols: 4
        malabaricone A: 3

Experts

1.	Bauri, Ajay K: 3 articles (10/2016 - 01/2015)
2.	Chatterjee, Mitali: 3 articles (10/2016 - 01/2015)
3.	Chattopadhyay, Subrata: 3 articles (10/2016 - 01/2015)
4.	Manna, Alak: 3 articles (10/2016 - 01/2015)
5.	De Sarkar, Sritama: 2 articles (10/2016 - 07/2015)
6.	De, Soumita: 2 articles (10/2016 - 07/2015)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2015 - "The cytotoxicity of Malabaricone-A (MAL-A), a diarylnonanoid derived from Myristica malabarica was demonstrated in leukemic cell lines, but its effectiveness in drug-resistant cancer cell lines has not been evaluated. " 10/01/2016 - "Intrinsically cancer cells have higher basal levels of reactive oxygen species (ROS), which when augmented by pro-oxidants such as Malabaricone-A (MAL-A) triggers apoptotic cell death, secondary to 'turning on' of the apoptosis related cell signaling pathways. " 07/15/2015 - "Intrinsically, cancer cells have higher basal levels of ROS which if supplemented by additional oxidative insult by pro-oxidants can be cytotoxic, an example being Malabaricone-A (MAL-A). "
2.	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 10/01/2016 - "Impact of MAPK and PI3K/AKT signaling pathways on Malabaricone-A induced cytotoxicity in U937, a histiocytic lymphoma cell line."

Related Drugs and Biologics

1.	Reactive Oxygen Species (Oxygen Radicals)