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genejammer

a gene transfection agent

Networked: 4 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Polyamines: 3918
    - genejammer: 4

Experts

1.	Konopka, Krystyna: 3 articles (01/2006 - 01/2005)
2.	Overlid, Nathan: 3 articles (01/2006 - 01/2005)
3.	Düzgünes, Nejat: 2 articles (12/2005 - 01/2005)
4.	Bosch, P: 1 article (11/2006)
5.	Davis, A R: 1 article (11/2006)
6.	Fouletier-Dilling, C: 1 article (11/2006)
7.	Olmsted-Davis, E A: 1 article (11/2006)
8.	Stice, S L: 1 article (11/2006)
9.	Düzgüneş, Nejat: 1 article (01/2006)
10.	Nagaraj, Anitha C: 1 article (01/2006)

Related Diseases

1.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 12/01/2005 - "In this study, the authors examined two novel gene transfection reagents, Metafectene and GeneJammer, for their ability to deliver a reporter gene to SCCVII murine squamous cell carcinoma cells in the presence of high concentrations of mouse serum. " 01/01/2006 - "Serum decreases the size of Metafectene-and Genejammer-DNA complexes but does not affect significantly their transfection activity in SCCVII murine squamous cell carcinoma cells."
2.	Squamous Cell Carcinoma of Head and Neck 01/01/2005 - "In this study we evaluated the effect of high concentrations (20-60%) of fetal bovine serum (FBS) on the transfection efficiency of two novel reagents, the polycationic liposome, Metafectene, and the polyamine reagent, GeneJammer, in HSC-3 and H357 human oral squamous cell carcinoma (OSCC) cells. "
3.	Mouth Neoplasms (Oral Cancer) 01/01/2005 - "Serum-resistant gene transfer to oral cancer cells by Metafectene and GeneJammer: application to HSV-tk/ganciclovir-mediated cytotoxicity." 01/01/2006 - "A relatively high efficiency of transfection could be achieved in human oral cancer cells transfected with the polycationic liposome, Metafectene, and the polyamine reagent, GeneJammer, in the presence of 60% fetal bovine serum (FBS) (Konopka et al., Cell. "
4.	Infections 11/01/2006 - "Addition of GeneJammer during adenoviral infection of pMSCs can revert the poor transduction efficiency of pMSCs while retaining their pluripotent differentiation capacity. "

Related Drugs and Biologics

1.	Indicators and Reagents (Reagents)
2.	metafectene
3.	Bovine Serum Albumin
4.	Polyamines
5.	Liposomes (Liposome)
6.	Ganciclovir (Cytovene)
7.	DNA (Deoxyribonucleic Acid)