3,4,5- tetrahydro- (2,3')bifuranyl- 5- yl)- pentan- 2- one 4-methyl-1-(5-methyl-2

from the leaves and stems of Bontia daphnoides L.; a cytotoxic agent; structure in first source

Also Known As:

4-methyl-1-(5-methyl-2, 3,4,5-tetrahydro-(2,3')bifuranyl-5-yl)-pentan-2-one; epingaione

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Sarcoma (Soft Tissue Sarcoma) 01/01/2007 - "In vitro anti-proliferation/cytotoxic activity of epingaione and its derivatives on the human SH-SY5Y neuroblastoma and TE-671 sarcoma cells."
2.	Neuroblastoma 01/01/2007 - "Both epingaione and compound 2 caused an accumulation of arrested or dead SH-SY5Y neuroblastoma in the m-phase of the cell cycle as revealed by the m-phase specific marker KE 67." 01/01/2007 - "In vitro anti-proliferation/cytotoxic activity of epingaione and its derivatives on the human SH-SY5Y neuroblastoma and TE-671 sarcoma cells."
3.	Neoplasms (Cancer) 01/01/2007 - "Epingaione was transformed into eleven derivatives under laboratory conditions using ethanol, some gave greater anti-proliferation/cytotoxic activity on the cancer cell lines tested. "

1.	Ethanol (Ethyl Alcohol)