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6-prenylnaringenin

from hop plant (Humulus lupulus): structure in first source

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        6-prenylnaringenin: 7
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        6-prenylnaringenin: 7

Experts

1.	Delmulle, L: 2 articles (02/2008 - 11/2006)
2.	Bartmańska, Agnieszka: 1 article (11/2018)
3.	Filip-Psurska, Beata: 1 article (11/2018)
4.	Milczarek, Magdalena: 1 article (11/2018)
5.	Popłoński, Jarosław: 1 article (11/2018)
6.	Tronina, Tomasz: 1 article (11/2018)
7.	Wietrzyk, Joanna: 1 article (11/2018)
8.	Deguchi, Takahiro: 1 article (01/2018)
9.	Fujita, Tomoyo: 1 article (01/2018)
10.	Horaguchi, Yamato: 1 article (01/2018)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 11/09/2018 - "Isoxanthohumol was more potent than cisplatin against breast cancer cell lines MDA-MB-231 and T-47D whereas 6-prenylnaringenin was stronger than cisplatin against breast cancer cell line T-47D. " 09/01/2005 - "In the current study, we tested the effects of the hop-derived compounds 8-prenylnaringenin, 6-prenylnaringenin, xanthohumol and isoxanthohumol (1) to modulate markers of differentiation and gene expression in osteoblasts and (2) to regulate proliferation in MCF-7 breast cancer cells. "
2.	Prostatic Neoplasms (Prostate Cancer) 06/01/2015 - "Here, we investigated the possible anti-cancer potential of 6-prenylnaringenin (6-PN) and 8-prenylnaringenin (8-PN), two prenylflavonoids present in hops and beer and demonstrate an unexpectedly pronounced, dose-dependent reduction of cellular proliferation of human PC-3 prostate cancer and UO.31 renal carcinoma cells upon treatment. " 02/01/2008 - "Xanthohumol (X), isoxanthohumol (IX), 8-prenylnaringenin (8PN) and 6-prenylnaringenin (6PN), prenylflavonoids from hop (Humulus lupulus L.), were investigated for their cytotoxicity and the mechanism by which they exert cell death when incubated with prostate cancer cell lines PC-3 and DU145. " 11/01/2006 - "Chalcones xanthohumol (X) and desmethylxanthohumol (DMX), present in hops (Humulus lupulus L.), and the corresponding flavanones isoxanthohumol (IX, from X), 8-prenylnaringenin (8-PN, from DMX), and 6-prenylnaringenin (6-PN, from DMX), have been examined in vitro for their anti-proliferative activity on human prostate cancer cells PC-3 and DU145. "
3.	Neoplasms (Cancer) 06/01/2015 - "Here, we investigated the possible anti-cancer potential of 6-prenylnaringenin (6-PN) and 8-prenylnaringenin (8-PN), two prenylflavonoids present in hops and beer and demonstrate an unexpectedly pronounced, dose-dependent reduction of cellular proliferation of human PC-3 prostate cancer and UO.31 renal carcinoma cells upon treatment. " 06/01/2012 - "Further, lupulone C (2) and 6-prenylnaringenin (14) exhibited inhibitory effects on skin-tumor promotion in an in vivo two-stage mouse-skin carcinogenesis test based on 7,12-dimethylbenz[a]anthracene (DMBA) as initiator and with TPA as promoter." 11/09/2018 - "Xanthohumol (XN) and four minor hops prenylflavonoids: α,β-dihydroxanthohumol (2HXN), isoxanthohumol (IXN), 8-prenylnaringenin (8PN), and 6-prenylnaringenin (6PN), were tested for antiproliferative activity towards human cancer and normal cell lines. "
4.	Carcinogenesis 06/01/2012 - "Further, lupulone C (2) and 6-prenylnaringenin (14) exhibited inhibitory effects on skin-tumor promotion in an in vivo two-stage mouse-skin carcinogenesis test based on 7,12-dimethylbenz[a]anthracene (DMBA) as initiator and with TPA as promoter."
5.	Visceral Pain 01/01/2018 - "Blockade of T-type calcium channels by 6-prenylnaringenin, a hop component, alleviates neuropathic and visceral pain in mice."

Related Drugs and Biologics

1.	8-prenylnaringenin
2.	isoxanthohumol
3.	xanthohumol
4.	Chalcones
5.	Flavanones
6.	T-Type Calcium Channels (T-Type Calcium Channel)
7.	Cisplatin (Platino)
8.	anthracene
9.	lupulon