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13,17- bis(1- carboxyethyl)- 8- (2- (2,4- dichlorophenylhydrazono)ethylidene)- 3- ethenyl- 7- hydroxy- 2,7,12,18- tetramethylchlorin

putative agent for sonodynamic therapy; structure in first source

Also Known As:

DCPH-P-Na(I)

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - Tetrapyrroles: 70
        Porphyrins: 3316
        13,17-bis(1-carboxyethyl)-8-(2-(2,4-dichlorophenylhydrazono)ethylidene)-3-ethenyl-7-hydroxy-2,7,12,18-tetramethylchlorin: 2
- Fused-Ring Heterocyclic Compounds
  - 4 or More Rings Heterocyclic Compounds
    - Tetrapyrroles: 70
      - Porphyrins: 3316
        13,17-bis(1-carboxyethyl)-8-(2-(2,4-dichlorophenylhydrazono)ethylidene)-3-ethenyl-7-hydroxy-2,7,12,18-tetramethylchlorin: 2
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Tetrapyrroles: 70
    - Porphyrins: 3316
      - 13,17-bis(1-carboxyethyl)-8-(2-(2,4-dichlorophenylhydrazono)ethylidene)-3-ethenyl-7-hydroxy-2,7,12,18-tetramethylchlorin: 2
Biological Factors: 2472
- Biological Pigments: 1
  - Porphyrins: 3316
    - 13,17-bis(1-carboxyethyl)-8-(2-(2,4-dichlorophenylhydrazono)ethylidene)-3-ethenyl-7-hydroxy-2,7,12,18-tetramethylchlorin: 2

Experts

1.	Sakata, Isao: 2 articles (06/2010 - 06/2007)
2.	Ikeda, Toshihiko: 1 article (06/2010)
3.	Iwase, Yumiko: 1 article (06/2010)
4.	Momose, Yasunori: 1 article (06/2010)
5.	Nishi, Koji: 1 article (06/2010)
6.	Umemura, Shin-Ichiro: 1 article (06/2010)
7.	Yumita, Nagahiko: 1 article (06/2010)
8.	Asano, Ryuji: 1 article (06/2007)
9.	Hachimine, Ken: 1 article (06/2007)
10.	Kinugasa, Tetsushi: 1 article (06/2007)

Related Diseases

1.	Neoplasms (Cancer) 06/01/2007 - "In addition, in a mouse xenograft model, a potent growth inhibition of the tumor was observed using sonication after the administration of DCPH-P-Na(I) to the mouse. " 06/01/2007 - "DCPH-P-Na(I) demonstrated significant sonotoxicity against a variety of cancer cell lines derived from different tissues. " 06/01/2007 - "However, DCPH-P-Na(I) exhibited a potent sonotoxicity on tumor cells by irradiation with ultrasound in vitro. " 06/01/2007 - "These results suggest that sonodynamic therapy with DCPH-P-Na(I) may therefore be a useful clinical treatment for cancers located deep in the human body without inducing skin sensitivity, which tends to be a major side-effect of photosensitizers." 06/01/2007 - "Sonodynamic therapy of cancer using a novel porphyrin derivative, DCPH-P-Na(I), which is devoid of photosensitivity."
2.	Phototoxic Dermatitis (Phototoxicity) 06/01/2007 - "According to this observation, when human tumor cells were exposed to light in the presence of DCPH-P-Na(I) in vitro, the least phototoxicity was observed, in contrast to the strong phototoxicity of ATX-70. "
3.	Sarcoma 180 06/01/2010 - "Sarcoma 180 cells suspended in air-saturated PBS were exposed to ultrasound at 2 MHz for up to 60 s in the presence and absence of DCPH-P-Na(I). "

Related Drugs and Biologics

1.	Photosensitizing Agents (Photosensitizers)
2.	Porphyrins
3.	ATX 70

Related Therapies and Procedures

1.	Therapeutics