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benzyldihydroxyoctenone

antineoplastic agent isolated from Streptomyces; structure in first source

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Alcohols: 595
  - Fatty Alcohols: 172
    - Octanols: 2
      - benzyldihydroxyoctenone: 2
Lipids: 114793
- Fatty Alcohols: 172
  - Octanols: 2
    - benzyldihydroxyoctenone: 2

Experts

1.	Lee, Chul-Hoon: 2 articles (05/2011 - 02/2009)
2.	Oh, Ha Lim: 2 articles (05/2011 - 02/2009)
3.	Suh, Hyewon: 1 article (05/2011)
4.	Kim, Min Kyoung: 1 article (02/2009)
5.	Kim, Young-Tae: 1 article (02/2009)
6.	Lim, Haeyoung: 1 article (02/2009)
7.	Moon, Hong Sang: 1 article (02/2009)
8.	Moon, Sangik: 1 article (02/2009)

Related Diseases

1.

Prostatic Neoplasms (Prostate Cancer)

02/01/2009 - "This study was aimed to evaluate detailed mechanisms on the apoptotic induction of benzyldihydroxyoctenone, a novel compound isolated from Streptomyces sp. KACC91015, in androgen-sensitive LNCaP prostate cancer cells. "
05/01/2011 - "The molecular mechanisms of apoptotic induction by benzyldihydroxyoctenone (BDH), a nonsteroidal antiandrogen, isolated from the culture broth of Streptomyces sp., have been previously published in prostate cancer LNCaP cells. "
05/01/2011 - "Benzyldihydroxyoctenone, a novel nonsteroidal antiandrogen, shows differential apoptotic induction in prostate cancer cells in response to their androgen responsiveness."
02/01/2009 - "Benzyldihydroxyoctenone, a novel anticancer agent, induces apoptosis via mitochondrial-mediated pathway in androgen-sensitive LNCaP prostate cancer cells."

Related Drugs and Biologics

1.	Androgens
2.	Antineoplastic Agents (Antineoplastics)
3.	Androgen Antagonists (Antiandrogens)